Results 11 to 20 of about 40,628 (317)
Multi-QTL mapping for quantitative traits using epistatic distorted markers. [PDF]
PLoS ONE, 2013 The interaction between segregation distortion loci (SDL) has been often observed in all kinds of mapping populations. However, little has been known about the effect of epistatic SDL on quantitative trait locus (QTL) mapping.
Shang-Qian Xie, Jia Wen, Yuan-Ming Zhang
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G3: Genes, Genomes, Genetics, 2018 We illustrate, through two case studies, that “mean-variance QTL mapping”—QTL mapping that models effects on the mean and the variance simultaneously—can discover QTL that traditional interval mapping cannot.
Robert W. Corty +4 more
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Estimating genetic variance contributed by a quantitative trait locus: A random model approach.
PLoS Computational Biology, 2022 Detecting quantitative trait loci (QTL) and estimating QTL variances (represented by the squared QTL effects) are two main goals of QTL mapping and genome-wide association studies (GWAS).
Shibo Wang, Fangjie Xie, Shizhong Xu
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Target Enrichment Improves Mapping of Complex Traits by Deep Sequencing
G3: Genes, Genomes, Genetics, 2016 Complex traits such as crop performance and human diseases are controlled by multiple genetic loci, many of which have small effects and often go undetected by traditional quantitative trait locus (QTL) mapping.
Jianjun Guo +3 more
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A robust QTL mapping procedure [PDF]
Journal of Statistical Planning and Inference, 2009 In quantitative-trait linkage studies using experimental crosses, the conventional normal location-shift model or other parameterizations may be unnecessarily restrictive. We generalize the mapping problem to a genuine nonparametric setup and provide a robust estimation procedure for the situation where the underlying phenotype distributions are ...
Zou, Fei +3 more
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Tools for quantitative trait locus mapping and genome-wide association study mapping: a review
浙江大学学报. 农业与生命科学版, 2014 One of the key objectives in genomics studies is to understand genetic architecture of complex traits and diseases. Quantitative trait locus (QTL) mapping and genome-wide association study (GWAS) mapping have been using to dissect genetic architecture of
Md. Mamun Monir, Zhu Jun
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Identification of unconditional and conditional QTL for oil, protein and starch content in maize
Crop Journal, 2013 Oil, protein and starch are key chemical components of maize kernels. A population of 245 recombinant inbred lines (RILs) derived from a cross between a high-oil inbred line, By804, and a regular inbred line, B73, was used to dissect the genetic ...
Yuqiu Guo +6 more
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Trends in Genetics, 1995 In the past 10 years, interest in applying the tools of molecular genetics to the problem of increasing world rice production has resulted in the generation of two highly saturated, molecular linkage maps of rice, and the localization of numerous genes and quantitative trait loci (QTLs).
S R, McCouch, R W, Doerge
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Composite Interval Mapping Based on Lattice Design for Error Control May Increase Power of Quantitative Trait Locus Detection. [PDF]
PLoS ONE, 2015 Experimental error control is very important in quantitative trait locus (QTL) mapping. Although numerous statistical methods have been developed for QTL mapping, a QTL detection model based on an appropriate experimental design that emphasizes error ...
Jianbo He +6 more
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Journal of Lipid Research, 2013 In the past 15 years, the quantitative trait locus (QTL) mapping approach has been applied to crosses between different inbred mouse strains to identify genetic loci associated with plasma HDL cholesterol levels.
Cheryl Ackert-Bicknell +2 more
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