Results 41 to 50 of about 29,942 (267)

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

eQTL Catalogue 2023: New datasets, X chromosome QTLs, and improved detection and visualisation of transcript-level QTLs.

PLoS Genetics, 2023
The eQTL Catalogue is an open database of uniformly processed human molecular quantitative trait loci (QTLs). We are continuously updating the resource to further increase its utility for interpreting genetic associations with complex traits.
Nurlan Kerimov, Ralf Tambets, James D Hayhurst, Ida Rahu, Peep Kolberg, Uku Raudvere, Ivan Kuzmin, Anshika Chowdhary, Andreas Vija, Hans J Teras, Masahiro Kanai, Jacob Ulirsch, Mina Ryten, John Hardy, Sebastian Guelfi, Daniah Trabzuni, Sarah Kim-Hellmuth, William Rayner, Hilary Finucane, Hedi Peterson, Abayomi Mosaku, Helen Parkinson, Kaur Alasoo   +22 more
doaj   +1 more source

QTL mapping in rice

Trends in Genetics, 1995
In the past 10 years, interest in applying the tools of molecular genetics to the problem of increasing world rice production has resulted in the generation of two highly saturated, molecular linkage maps of rice, and the localization of numerous genes and quantitative trait loci (QTLs).
S R, McCouch, R W, Doerge
openaire   +2 more sources

An Artificially Selected Cytokinin‐Pathway Transcription Factor Balances Soybean Yield and Pathogen Resistance

Advanced Science, EarlyView.
A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma, Yaqing Chen, Yiwen Gao, Xueting Hu, Qun Yang, Yucheng Liu, Peiyong Xin, Jijun Yan, Jinfang Chu, Lei Li, Zhixi Tian, Bo Ren   +11 more
wiley   +1 more source

Mapping QTL for Grain Yield under Moisture Stress Environments in Rice (Oryza sativa L.)

Notulae Scientia Biologicae, 2011
Polygenes (QTLs) for grain yield were mapped on rice chromosomes under two moisture stress environments by multiple interval mapping (MIM) method in a double haploid (DH) population derived from a cross between a deep-rooted japonica and a shallow-rooted
Supriyo CHAKRABORTY, Sheng-Chu WANG, Zhao-Bang ZENG   +2 more
doaj   +3 more sources

Conditional QTL Mapping of Sedimentation Volume on Seven Quality Traits in Common Wheat

Journal of Integrative Agriculture, 2013
To evaluate the possible genetic interrelationships between flour components and the sedimentation volume (SD), a doubled haploid (DH) population comprising 168 lines were used to identify the conditional quantitative trait loci (QTLs) for SD in three ...
Zhi-ying DENG, Liang ZHAO, Bin LIU, Kun-pu ZHANG, Jian-sheng CHEN, Hou-lan QU, Cai-ling SUN, Yong-xiang ZHANG, Ji-chun TIAN   +8 more
doaj   +1 more source

Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective

Advanced Science, EarlyView.
Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang, Chenhui Li, Dongjiao Wang, Qibin Wu, Zhen Zeng, Huiming Guo, Han Cheng, Songbi Chen, Hongxing Cao, Hongmei Cheng, Jianghui Xie, Youxiong Que   +11 more
wiley   +1 more source

Multiomic QTL mapping reveals phenotypic complexity of GWAS loci and prioritizes putative causal variants

Cell Genomics
Summary: Most GWAS loci are presumed to affect gene regulation; however, only ∼43% colocalize with expression quantitative trait loci (eQTLs). To address this colocalization gap, we map eQTLs, chromatin accessibility QTLs (caQTLs), and histone ...
Timothy D. Arthur, Jennifer P. Nguyen, Benjamin A. Henson, Agnieszka D'Antonio-Chronowska, Jeffrey Jaureguy, Nayara Silva, Athanasia D. Panopoulos, Juan Carlos Izpisua Belmonte, Matteo D’Antonio, Graham McVicker, Kelly A. Frazer, Angelo D. Arias, Paola Benaglio, W. Travis Berggren, Victor Borja, Megan Cook, Christopher DeBoever, Kenneth E. Diffenderfer, Margaret K.R. Donovan, KathyJean Farnam, Kyohei Fujita, Melvin Garcia, Olivier Harismendy, David Jakubosky, Kristen Jepsen, Isaac Joshua, He Li, Hiroko Matsui, Angelina McCarron, Naoki Nariai, Daniel T. O’Connor, Jonathan Okubo, Fengwen Rao, Joaquin Reyna, Lana Ribeiro Aguiar, Bianca M. Salgado, Nayara Silva, Erin N. Smith, Josh Sohmer, Shawn Yost, William W. Young Greenwald   +40 more
doaj   +1 more source

Identification of quantitative trait loci (QTLs) and candidate genes for seed shape and 100-seed weight in soybean [Glycine max (L.) Merr.]

Frontiers in Plant Science, 2023
Seed size and shape are important traits determining yield and quality in soybean. Seed size and shape are also desirable for specialty soy foods like tofu, natto, miso, and edamame.
Rahul Kumar, Manisha Saini, Meniari Taku, Pulak Debbarma, Rohit Kumar Mahto, Rohit Kumar Mahto, Ayyagari Ramlal, Deepshikha Sharma, Ambika Rajendran, Renu Pandey, Kishor Gaikwad, S. K. Lal, Akshay Talukdar   +12 more
doaj   +1 more source