Results 1 to 10 of about 150,397 (174)

Challenging the Bredt’s rule in an acid catalyzed cationic cyclization to get bicyclo[3.3.1]nonane derivatives [PDF]

open access: yesNature Communications
Vinyl carbocations are long known in chemistry but remain less explored than common sp²-hybridized carbocations, and their synthetic applications are limited.
Olaya García-Pedrero   +4 more
doaj   +2 more sources

Enantioselective total synthesis of putative dihydrorosefuran, a monoterpene with an unique 2,5-dihydrofuran structure

open access: yesBeilstein Journal of Organic Chemistry, 2022
An original synthesis of the structure of dihydrorosefuran, a compound allegedly identified in Artemisia pallens and Tagetes mendocina, has been developed.
Irene Torres-García   +5 more
doaj   +1 more source

Enantioselective Synthesis of a New Non-Natural Gabosine

open access: yesMolecules, 2021
The preparation of a new non-natural gabosine is reported, in which the chirality is transferred from the toluene’s biotransformed metabolite (1R,2S)-3-methylcyclohexa-3.5-diene-1,2-diol.
Maximiliano Colobbio   +2 more
doaj   +1 more source

Synthesis and Modeling of Ezetimibe Analogues

open access: yesMolecules, 2021
Ezetimibe is a well-known drug that lowers blood cholesterol levels by reducing its absorption in the small intestine when joining to Niemann-Pick C1-like protein (NPC1L1).
Mateo M. Salgado   +4 more
doaj   +1 more source

Iboga Inspired N-Indolylethyl-Substituted Isoquinuclidines as a Bioactive Scaffold: Chemoenzymatic Synthesis and Characterization as GDNF Releasers and Antitrypanosoma Agents

open access: yesMolecules, 2022
The first stage of the drug discovery process involves the identification of small compounds with biological activity. Iboga alkaloids are monoterpene indole alkaloids (MIAs) containing a fused isoquinuclidine-tetrahydroazepine ring.
Mariana Pazos   +6 more
doaj   +1 more source

Latest Trends in Surface Modification for Dental Implantology: Innovative Developments and Analytical Applications

open access: yesPharmaceutics, 2022
An increase in the world population and its life expectancy, as well as the ongoing concern about our physical appearance, have elevated the relevance of dental implantology in recent decades. Engineering strategies to improve the survival rate of dental
Francesca Accioni   +4 more
doaj   +1 more source

Silicone-specific identification of trace polydimethylsiloxanes in wines with 2D-diffusion-ordered nuclear magnetic resonance spectroscopy (DOSY-NMR)

open access: yesBIO Web of Conferences, 2023
Present work stresses a novel analytical approach for increasing the specificity of standard NMR approaches for identifying polydimethylsiloxane (PDMS) and further silicone moieties in wines’ organic extracts, by including a second dimension that ...
Herbert-Pucheta José Enrique   +5 more
doaj   +1 more source

Synthesis, anti-tuberculosis activity and QSAR study of 2,4-diarylquinolines and analogous polycyclic derivatives [PDF]

open access: yes, 2019
The multicomponent syntheses of 2,4-di-aryl-quinolines and analogous polycyclic derivatives as anti-tuberculosis agents were described. They were prepared via Beyer and Friedländer methods under microwave irradiation in short reaction times and good ...
Asís, Silvia Elizabeth   +7 more
core   +1 more source

Surfactants. XX. Fatty ω-monoesters of dithíoacetals of sugars

open access: yesGrasas y Aceites, 1995
The preparation of 5-O-lauroyl(myhstoyl, palmitoyl)-D-arabinose ethylendithioacetals, 6-O-lauroyl-D-glucose(D-galactose) ethylendithioacetals and 6-O-decanoyl(lauroyl)-D-mannose ethylendithioacetals is reported.
J. Fernández-Bolaños   +2 more
doaj   +1 more source

Tuneable Acidity in Fluorinated Al-SBA-15 Materials for the Esterification of Valeric Acid to Alkyl Valerates

open access: yesFrontiers in Chemistry, 2020
The acidity of Al-SBA-15 materials functionalized by ball milling with several niobium loadings (0. 25–1 wt.%) as well as with several fluorine loadings (by wet impregnation using NH4F as a precursor) was characterized and materials investigated in the ...
Miguel Blanco-Sánchez   +6 more
doaj   +1 more source

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