Results 91 to 100 of about 108,024 (198)

MGL‐Based Drug Conjugate: A Novel Glycan‐Targeting Strategy for Potential Precision Cancer Therapy

ChemistryEurope, Volume 4, Issue 5, May 2026.
An engineered macrophage galactose‐type lectin (MGL)‐based conjugate (mMGL‐vcMMAE), incorporating an exposed cysteine for site‐specific drug linkage, preserves stability, binding profile, and affinity of the native MGL carbohydrate recognition domain. It also selectively targets Tn/STn‐expressing cancer cells and shows recognition of colorectal cancer ...
Carlos D. L. Lima, Rafaela Abrantes, Victor Lorrain, Joana Gomes, Reyes Núñez‐Franco, João P. M. António, Catarina Gomes, Ana Gimeno, Benedita A. Pinheiro, Angelina S. Palma, Jesús Jiménez‐Barbero, Pedro M. P. Gois, Gonzalo Jiménez‐Osés, Sandra J. van Vliet, Celso A. Reis, Filipa Marcelo   +15 more
wiley   +1 more source

Magnetism for the Quantification of Sorption in Porous Materials From Liquid Media

Chemistry–Methods, Volume 6, Issue 5, May 2026.
This adsorption quantification technique uses external magnetic fields and a magnetic holder to measure mass changes during adsorption, making it universally applicable to any adsorbate. Unlike standard methods, it requires calibration only for the adsorbent rather than for every analyte.
Rubén Pérez‐Aguirre, Garikoitz Beobide, Oscar Castillo   +2 more
wiley   +1 more source

Effect of solarization, chemical and organic fertilization on the control of nematode on greenhouse lettuce [PDF]

, 2006
Os efeitos da solarização do solo associados à adubação no controle de nematóides e na produtividade da alface cultivar "Verônica" foram avaliados em solo naturalmente infestado. Dois experimentos foram conduzidos, um com e outro sem solarização, em casa
Junqueira, Ana Maria Resende, Oliveira, Charles Martins de, Sharma, Ravi Datt, Silva, Marlene Gonçalves da   +3 more
core   +1 more source

Monovalent mannose‐glycoconjugates of sulforaphane reprogram human dendritic cells via NFATc1 to induce immune tolerance under inflammatory conditions

British Journal of Pharmacology, Volume 183, Issue 9, Page 1993-2008, May 2026.
Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez, Camila Leiva‐Castro, Ana M. Múnera‐Rodríguez, Macarena Martínez‐Bailén, Ana T. Carmona, Soledad López‐Enríquez, Francisca Palomares   +6 more
wiley   +1 more source

Didactic sequence to teach laboratory techniques in organic chemistry: analysis of terpenes in common medicines

Educación Química
This work presents a didactic sequence (DS) for teaching key laboratory techniques—continuous and discontinuous extraction, vacuum and atmospheric distillation, steam extraction, and thin-layer chromatography (TLC)—to first-year organic chemistry ...
Brenda de Moraes Cordeiro, Carlos Magno Rocha Ribeiro   +1 more
doaj   +1 more source

Precisiones al artículo: “Conceptos básicos y mecanismos de reacción en la Química Orgánica”: Flevorio, Fl, y Livermorio, Lv, dos nuevos elementos aprobados por la IUPAC

Educación Química, 2018
Escribimos esta carta con el fin de señalar algunas imprecisiones y de hacer algunos agregados al artículo sobre mecanismos de reacción en la Química Orgánica aparecido en el Vol. 23, Núm. 2, pp. 205-207, 2012 de Educación Química.
Rosa María Aguilar-Garduño, Enrique González-Vergara, Aarón Pérez-Benítez   +2 more
doaj   +1 more source

Métodos de fracionamento e caracterização da matéria orgânica do solo. [PDF]

, 2019
bitstream/item/32410/1/documento-106 ...
MARTIN NETO, L., MIELNICZUK, J., PILLON, C. N.   +2 more
core   +1 more source

Efeitos da adubação orgânica e da época de colheita na qualidade da matéria-prima e nos rendimentos agrícola e de açúcar mascavo artesanal de duas cultivares de cana-de-açúcar (cana-planta). [PDF]

, 2007
Conduziu-se este trabalho com o objetivo de estudar os efeitos de três sistemas de adubação (30 t. ha-1 de esterco de curral, 3,5 t.ha-1 de esterco de galinha e adubação química - 120 kg.ha-1 de P2O5 e de K2O no plantio + 60 kg.ha-1 de N em cobertura) e ...
ANDRADE L. A. B., ANJOS I. A., ARIZONO H., DELGADO A. A., Gabriel José de Carvalho, Ivan Antônio dos Anjos, Julio César Garcia, Luiz Antônio de Bastos Andrade, MATSUOKA S., Paulo Alexandre Monteiro de Figueiredo, RAIZER A. J.   +10 more
core   +4 more sources

Synthetic Implications of Spin States in the Reactivity of Ni Intermediate Complexes in Coupling Reactions

European Journal of Organic Chemistry, Volume 29, Issue 16, 25 April 2026.
The formation of triplet Ni(II) complexes by activation of bromoalkenes with alkyl‐ or boryl Ni(I) is key to control the outcome of the reductive cross‐coupling of bromoalkanes precluding the formation of alkylboronates. We present a mechanistic study on the Ni‐catalyzed cross‐coupling reaction of bromoalkanes with diboron compounds as reductants.
Diego J. Cárdenas
wiley   +1 more source

HPW-Catalyzed environmentally benign approach to imidazo[1,2-a]pyridines

Beilstein Journal of Organic Chemistry
The imidazo[1,2-a]pyridine moiety is present in drugs with several biological activities. The most direct way of obtaining this nucleus is the Groebke–Blackburn–Bienaymé three-component reaction (GBB-3CR) between aminopyridines, aldehydes, and ...
Luan A. Martinho, Carlos Kleber Z. Andrade   +1 more
doaj   +1 more source