Results 71 to 80 of about 107,424 (195)

Mechanistic Paths for the Gold(I)‐Catalyzed Heteroannulation of Salicylic Amides With Apolar Alkynes Explored With Density Functional Theory Calculations

European Journal of Organic Chemistry, EarlyView.
A manifold of catalytic reaction paths can operate in the Au(I)‐catalyzed heteroannulation of salicylic amides and alkynes. However, a subtle initial nucleophilic advantage of N versus O and a kinetic bottleneck at an advanced stage of the mechanistic machinery seems to suffice for the reaction to run on a single path and with exquisite selectivity. We
Ioannis Stylianakis, Evaggelia Vlachou, Carlos Silva López, Antonios Kolocouris   +3 more
wiley   +1 more source

Carboxyxanthones: Bioactive Agents and Molecular Scaffold for Synthesis of Analogues and Derivatives

Molecules, 2019
Xanthones represent a structurally diverse group of compounds with a broad range of biological and pharmacological activities, depending on the nature and position of various substituents in the dibenzo-γ-pyrone scaffold.
João Ribeiro, Cláudia Veloso, Carla Fernandes, Maria Elizabeth Tiritan, Madalena M. M. Pinto   +4 more
doaj   +1 more source

Viabilidade do emprego de ácido fluorídrico 10% para a remoção de íons paramagnéticos em amostras de solos e suas respectivas frações físicas [PDF]

, 2010
A utilização de efluentes de esgoto tratado na irrigação, ao invés de realizar a disposição deste subproduto nos cursos d'água tem sido uma alternativa antiga, popular e atrativa, com triplo propósito: tratamento complementar do efluente, fonte de água e
MARTIN-NETO, Ladislau, MELFI, Adolpho Jose, MONTES, Célia Regina, SANTOS, Larissa Macedo dos, SIMÕES, Marcelo Luiz   +4 more
core   +1 more source

Synthetic Implications of Spin States in the Reactivity of Ni Intermediate Complexes in Coupling Reactions

European Journal of Organic Chemistry, EarlyView.
The formation of triplet Ni(II) complexes by activation of bromoalkenes with alkyl‐ or boryl Ni(I) is key to control the outcome of the reductive cross‐coupling of bromoalkanes precluding the formation of alkylboronates. We present a mechanistic study on the Ni‐catalyzed cross‐coupling reaction of bromoalkanes with diboron compounds as reductants.
Diego J. Cárdenas
wiley   +1 more source

Métodos de fracionamento e caracterização da matéria orgânica do solo. [PDF]

, 2019
bitstream/item/32410/1/documento-106 ...
MARTIN NETO, L., MIELNICZUK, J., PILLON, C. N.   +2 more
core   +1 more source

Metal‐Free Electrophilic Borylative Cyclizations of Alkynes

The Chemical Record, EarlyView.
Metal‐free borylative cyclizations based on electrophilic alkyne activation by boron Lewis acids provide efficient access to borylated hetero‐ and carbocycles. Early studies using B(C6F5)3 displayed limited scope and application, whereas recent ClBcat‐ and BCl3‐based methods enable mild CB and CC/CX bond formation for the synthesis of cycles ...
Jaime Mateos‐Gil, Marcos Humanes, Manuel A. Fernández‐Rodríguez, Patricia García‐García   +3 more
wiley   +1 more source

Recent Synthetic Approaches towards Small Molecule Reactivators of p53

Biomolecules, 2020
The tumor suppressor protein p53 is often called “the genome guardian” and controls the cell cycle and the integrity of DNA, as well as other important cellular functions.
Jerson L. Silva, Carolina G. S. Lima, Luciana P. Rangel, Giulia D. S. Ferretti, Fernanda P. Pauli, Ruan C. B. Ribeiro, Thais de B. da Silva, Fernando C. da Silva, Vitor F. Ferreira   +8 more
doaj   +1 more source

Produção vegetal e de óleo essencial de boldo pequeno em função de fontes de adubos orgânicos. [PDF]

, 2018
A aplicação de fertilizantes orgânicos, em plantas medicinais e aromáticas, normalmente modifica positivamente a produção vegetal e de óleo essencial.
ALVES, P. B., BERTOLUCCI, S. K. V., BRANT, R. da S., NICULAU, E. dos S., PINTO, J. E. B. P., ROSAL, L. F.   +5 more
core  

Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy

Allergy, EarlyView.
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane, Maria Salas, Sara Benede, Maria J. Rodriguez‐Sanchez, Maria J. Rodriguez‐Sojo, Isabel M. Jiménez‐Sánchez, Gador Bogas, Ezequiel Perez‐Inestrosa, Cristobalina Mayorga, Juan L. Paris, Alba Rodríguez‐Nogales, María J. Torres, María I. Montañez   +12 more
wiley   +1 more source

Monovalent mannose‐glycoconjugates of sulforaphane reprogram human dendritic cells via NFATc1 to induce immune tolerance under inflammatory conditions

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez, Camila Leiva‐Castro, Ana M. Múnera‐Rodríguez, Macarena Martínez‐Bailén, Ana T. Carmona, Soledad López‐Enríquez, Francisca Palomares   +6 more
wiley   +1 more source