Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis +11 more
wiley +1 more source
Alternative Methods of Determining Hamstrings-to-Quadriceps Ratios: a Comprehensive Review
The hamstrings-to-quadriceps muscle strength ratio calculated by peak torque has been used as an important tool to detect muscle imbalance, monitor knee joint stability, describe muscle strength properties and functionality, and for lower extremity ...
Cassio V. Ruas +5 more
doaj +1 more source
The Effect of Quadriceps Weakness in Older Adults on Lower Extremity Muscle Function During Gait [PDF]
Osteoarthritis is a painful condition that generally causes patients to experience weak quadriceps, abnormal gait kinematics, and difficulty completing daily movements.
Wetli, Alaine
core
Integrating yoga into anatomy and clinical medicine education: A holistic approach to learning
Abstract Anatomical knowledge is fundamental for success in clinical settings. Unfortunately, anatomy education within professional health programs has experienced a continual decrease in contact hours and curricular content over the previous two decades, leading to deficits and potential gaps in anatomical science knowledge.
Dana Rohde +4 more
wiley +1 more source
Lower Limb Radiology of Distal Myopathy due to the S60F Myotilin Mutation [PDF]
Distal myopathies are a clinically and genetically heterogenous group of disorders in which the distal limb musculature is selectively or disproportionately affected.
Birchall, Daniel +8 more
core +1 more source
Abstract Patellofemoral instability remains a challenging condition, especially in skeletally immature patients, who are at increased risk of recurrence. The medial patellofemoral ligament has historically been the focus of surgical reconstruction; however, recent anatomic studies have also highlighted the medial quadriceps tendon–femoral ligament as ...
Lokman Kehribar +2 more
wiley +1 more source
Early Rehabilitation with Weight-bearing Standing-shaking-board Exercise in Combination with Electrical Muscle Stimulation after Anterior Cruciate Ligament Reconstruction [PDF]
The objective of early rehabilitation after anterior cruciate ligament (ACL) reconstruction is to increase the muscle strength of the lower extremities. Closed kinetic chain (CKC) exercise induces co-contraction of the agonist and antagonist muscles. The
Fujii, Toshihiro +4 more
core +1 more source
Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell +3 more
wiley +1 more source
Background Chronic kidney disease (CKD) is a catabolic condition associated with muscle wasting and dysfunction, which associates with morbidity and mortality.
Douglas W. Gould +6 more
doaj +1 more source
Clinimetrics: Quadriceps muscle ultrasound
Louise, Hansell, George, Ntoumenopoulos
openaire +2 more sources

