Results 201 to 210 of about 4,909 (260)

MYC in Oncogenesis and Therapeutic Implications

MedComm, Volume 7, Issue 8, August 2026.
The MYC oncogene family (c‐MYC, N‐MYC, L‐MYC) functions as a central transcriptional hub orchestrating cancer progression through multiple interconnected pathways. This graphical abstract illustrates MYC's role as a multidimensional regulator positioned at the nexus of tumor microenvironment remodeling, metabolic reprogramming, and therapeutic ...
Na Zhang, Li Wei, Cuiping Tang, Peilong Lai, Wenbin Zhong, Hua You   +5 more
wiley   +1 more source

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source

CITF1 interacts with FIT and regulates copper-iron crosstalk in Arabidopsis. [PDF]

Plant Cell
Chia JC, Liu X, Dey S, Yan J, Niu Y, Vatamaniuk OK.   +5 more
europepmc   +1 more source

Safety and efficacy of a feed additive consisting of an extract from the dried leaves of <i>Hedera helix</i> L. (common ivy extract) and thymol for all animal species and categories except poultry, ornamental birds and all aquatic animal species (FEFANA asbl). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Theodoridou K, Bastos ML, Benfenati E, Brantom P, Chesson A, Schlatter J, Westendorf J, Manini P, Dusemund B.   +22 more
europepmc   +1 more source

Mechanisms driving open-closed transitions and dimer stability of the large GTPases hGBP1 and hGBP5. [PDF]

Front Mol Biosci
Bundschuh BF, Loschwitz J, Strodel B.
europepmc   +1 more source

Snapshots of the dynamic basis of NTSR1 G protein subtype promiscuity. [PDF]

Nature
Vo AA, Modak A, Lu S, Blanchard SC, Lambert NA, Robertson MJ.   +5 more
europepmc   +1 more source

Identification of candidate mechanosensory transduction channels in the aquatic insect Protohermes xanthodes (Megaloptera: Corydalidae) by transcriptome analysis. [PDF]

J Insect Sci
Zhang Y, Zhang M, Li Z, Jiang L, Chen J, Zheng L, Zhao W, Wang X, Tan Y, Huang X, Wu Z.   +10 more
europepmc   +1 more source

The combined effects of Golden2-like 2 and Pseudo-Response Regulator 2 control the fruit pigmentation in pepper. [PDF]

Plant J
Lee S, Lee GM, Yoo HJ, Cho LH, Lee JM.
europepmc   +1 more source