Results 201 to 210 of about 6,291 (282)
ABSTRACT The communication of sustainable development is essential for higher education institutions (HEIs), which voluntarily prepare sustainability reports (SRs) to demonstrate commitment and inform strategic decision‐making. This study conducts a systematic literature review (SLR) to identify and analyze the challenges associated with implementing ...
Valerio Brescia +3 more
wiley +1 more source
Chemotaxis to plant defense compounds in phytopathogens. [PDF]
Genova R +8 more
europepmc +1 more source
Defining AV2‐1 as a novel pharmacological probe to target human and rodent TRPV2
Abstract Background and Purpose Transient receptor potential vanilloid 2 (TRPV2) is a non‐selective cation channel implicated in immune cell functions. However, progress in understanding TRPV2 has been limited by a lack of potent and selective pharmacological tools, particularly those targeting the human variant. We aimed to identify and characterise a
Andrea Leipe +6 more
wiley +1 more source
Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity. [PDF]
Jiang J +16 more
europepmc +1 more source
ABSTRACT Protoberberine alkaloids are a characteristic group of natural products in Coptis plants known for their notable pharmacological activities. However, the structural similarity and the substrate promiscuity of their biosynthetic enzymes have left the precise synthetic pathways remain unclarified, posing challenges to regulate product formation.
Jun Song +14 more
wiley +1 more source
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami +2 more
wiley +1 more source
Fine-Tuning of the Neuropeptide Y1 G Protein-Coupled Receptor by the Tryptophan<sup>6.48</sup> "Toggle Switch". [PDF]
Voitel M +7 more
europepmc +1 more source
Simple Guanosine—Amino Acid Hybrids as Low Molecular Weight Hydrogelators
Unexplored guanosine‐amino acid derivatives act as low molecular weight hydrogelators. Gelation is triggered by K+ ions and pH changes and relies on G‐quadruplex formation. Small changes in the amino acid structure have a strong impact on the mechanical properties of the gels.
Silvia Pieraccini +6 more
wiley +1 more source
Viral pathogens in the etiology of acute respiratory infections in Bulgaria during the 2024-2025 season and genetic diversity of circulating influenza viruses. [PDF]
Korsun N +9 more
europepmc +1 more source
Semi‐rational engineering yields a thermostable Bacillus simplex formate dehydrogenase variant (Q125F) with a 25‐fold longer half‐life at 60°C and strong resistance to chemo‐inactivation. Molecular dynamics reveal enhanced π–π interactions stabilizing a flexible loop and enabling efficient NADH regeneration for robust biocatalytic detoxification ...
Rattima Boonkumkrong +7 more
wiley +1 more source

