Results 141 to 150 of about 244,037 (301)

Development of an Independent Regulatory Council for the International Qualification Framework: International Universities Strength and Conditioning Association Position Statement

The establishment of the International Qualification Framework (IQF) represented a seminal advancement towards standardising education and certification levels in the profession of strength and conditioning (S&C).
Aden Flannagan, Stephen P. Bird, Bird, Stephen P., Paulo Marchetti, Andrew Langford, Langford, Andrew, Marchetti, Paulo, Timothy J. Piper, Morley, David, David Morley, Flannagan, Aden, Piper, Timothy J.   +11 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Correction: Telemedicine via data glasses in CBRN protection suit-Evaluation of medical qualification and technical feasibility. [PDF]

PLoS One
Bovenkerk S, Mueller A, Rossaint R, Czaplik M, Follmann A.   +4 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Accreditation and qualification of primary care teaching practices in Germany - a nationwide online survey of universities. [PDF]

GMS J Med Educ
Gehrke-Beck S, Kitte I, Streitlein-Böhme I, Deutsch T, Demmer I, Gornostayeva M, Jendyk R.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Qualification of a quantitative stability indicating potency assay for mRNA-LNP vaccine candidates. [PDF]

Gates Open Res
Bzami A, Estrada M, Schofield T, White JA.   +3 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Qualification Test

, 1956
Air Force ROTC Cadets during a qualification test ...

core  

DIF: Concepts, Measurement, and Impact in Patient-Focused Drug Development and Regulatory Decision-Making. [PDF]

Drug Des Devel Ther
Cao K, Liu W, Yang L, Luo M, Hou Y.
europepmc   +1 more source