Results 111 to 120 of about 891,174 (285)
Guidance on Qualification Titles within the Qualifications and Credit Framework [PDF]
, 2010 Feedback on the implementation of the Regulatory arrangements for the Qualifications and Credit Framework (Ofqual/08/3726) governing titling within the QCF indicates that further guidance is necessary on particular issues raised by awarding organisations
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FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
La Grande Illusion : why Scottish further education has failed to grasp the potential of modern languages [PDF]
, 2011 The most recently available data from the Scottish Qualifications Authority show that modern language provision in the Scottish further education sector is on the verge of a total collapse.
Doughty, Hannelore
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, 2019 “Qualification” is a poetic exegesis which proposes to reclaim the act of writing for its own art and away from the nullifying structures of the academic text. It comprises of a series of writings which have engaged with their context, in particular the administration that concedes so much of the labour of the contemporary artist, a concession common ...
openaire +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Abnormal location of the portal vein as a cause of duodenal obstruction in adults
Вестник хирургии имени И.И. ГрековаThe preduodenal portal vein, being an extremely rare anomaly that occurs with a frequency of 3:1000, is clinically manifested mainly in childhood by signs of intestinal obstruction due to duodenal compression. In adults, this anomaly is asymptomatic, but
A. B. Fatikh +3 more
doaj
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source