Results 101 to 110 of about 908,678 (344)

La Grande Illusion : why Scottish further education has failed to grasp the potential of modern languages [PDF]

open access: yes, 2011
The most recently available data from the Scottish Qualifications Authority show that modern language provision in the Scottish further education sector is on the verge of a total collapse.
Doughty, Hannelore
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Factors and criteria determining career advancement in the Polish police - internal stakeholders' perspective

open access: yesJournal of Modern Science
Objectives The purpose of the article and the research conducted is to identify the factors and criteria determining promotion in the Police. Material and methods The research used the diagnostic survey method, survey research technique and an original ...
Bogdan Nogalski   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

THE PROBATIONARY PERIOD FOR A FIXED-TERM EMPLOYMENT CONTRACT

open access: yesВестник университета, 2019
In the article the peculiarities of concluding a fixed term employment contract when hiring employees whose job is temporary, seasonal. Therefore, the analysis of the duration of the probationary period, noted some categories of people having the right ...
T. Suvalova
doaj  

China-ASEAN Qualifications Framework: Pathways to mutual recognition

open access: diamond, 2023
Bohong Li   +8 more
openalex   +2 more sources

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