Results 111 to 120 of about 165,724 (306)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mature women and the New Zealand qualifications framework. realising the potential of recognising prior learning [PDF]

open access: yes, 2003
Against a backtground of 'second-wave' lifelong learning in Aotearoa New Zealand a new framework for post-compulsory national qualfications was introduced. The restulting competency-based system was argued to present a number of benefits for mature women
Annelies Kamp, Kamp, Annelies
core  

THE PROBATIONARY PERIOD FOR A FIXED-TERM EMPLOYMENT CONTRACT

open access: yesВестник университета, 2019
In the article the peculiarities of concluding a fixed term employment contract when hiring employees whose job is temporary, seasonal. Therefore, the analysis of the duration of the probationary period, noted some categories of people having the right ...
T. Suvalova
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Information about occupations in the activityof the regional labour office [PDF]

open access: yesEdukacja Ustawiczna Dorosłych, 2019
One of the tasks carried out by the Regional Labour Offices in Poland is the coordination and provision of career guidance and career information services as well as activities in the field of international job placement within the framework of the EURES
Anna Kicior
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The "home international" comparisons in vocational qualifications

open access: yes, 2002
The paper provides a comparative analysis of the take-up and usage of National Vocational Qualifications within two constituent countries in the UK (Scotland and England).
Canning, Roy   +3 more
core   +1 more source

Craft vocational training on the example of selected descriptions about occupations [PDF]

open access: yesEdukacja Ustawiczna Dorosłych, 2019
On the Polish ground there are currently 132 professions corresponding to a given type of craft in a dozen or so branches. They are characterized by pluriformity of hard, i.e.
Andrzej Wojciech Stępnikowski
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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