Results 41 to 50 of about 20,113,391 (246)

Fundamental Measurement: The Need Fulfilment Quality of Life (N-QOL) Measure

INNOVATIONS in Pharmacy, 2021
The quality adjusted life year (QALY) has serious problems related to its failure to adhere to measurement theory. If a QALY is to be meaningful, the utility score that translates time spent to an equivalent time spent in so-called perfect health must ...
Paul C. Langley, Stephen P. McKenna
doaj   +1 more source

Justifying Terminal Care by 'Retrospective Quality-Adjusted Life-Years'

, 2010
A lot of medical procedures can be justified in terms of the number of quality-adjusted life-years (QALYs) they can be expected to generate; that is, the number of extra years that the procedure will provide, with the quality of life during those extra ...
Cowley, Christopher
core   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

The Proposal and Application of Quality-adjusted Life Years

Yixue yu zhexue
Quality-adjusted life years (QALYs) is a quantitative health measure that integrates both life expectancy and quality, proposed in the 1970s as an effective tool for aiding the rational allocation of healthcare resources while balancing efficiency and ...
Yixuan LI
doaj   +1 more source

Utility Weights for Allergic Rhinitis Based on a Community Survey with a Time Trade-off Technique in Japan

Allergology International, 2009
Background: Allergic rhinitis is not a fatal disease, but its symptoms deteriorate the quality of life. High morbidity raises a concern about its impact on health care resources.
Kazuhiro Tamayama, Masahide Kondo, Aiko Shono, Ichiro Okubo   +3 more
doaj   +1 more source

Disparities in total knee replacement: Population losses in quality-adjusted life years due to differential offer, acceptance, and complication rates for Black Americans

Arthritis care & research, 2018
Total knee replacement (TKR) is an effective treatment for end‐stage knee osteoarthritis (OA). American racial minorities undergo fewer TKRs than whites.
Hannah M. Kerman, Savannah R. Smith, Karen C. Smith, J. Collins, L. Suter, J. N. Katz, E. Losina   +6 more
semanticscholar   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Measuring the impact of alcohol-related disorders on quality of life through general population preferences

Gaceta Sanitaria, 2017
Objective: To estimate the intangible effects of alcohol misuse on the drinker's quality of life, based on general population preferences Methods: The most important effects (dimensions) were identified by means of two focus groups conducted with ...
Eva Rodríguez-Míguez, Jacinto Mosquera Nogueira   +1 more
doaj   +1 more source

Are Quality-Adjusted Life Years a Good Proxy Measure of Individual Capabilities?

PharmacoEconomics (Auckland), 2017
BackgroundThere is a debate in the health economics literature concerning the most appropriate way of applying Amartya Sen’s capability approach in economic evaluation studies.
P. Mitchell, S. Venkatapuram, J. Richardson, Angelo Iezzi, J. Coast   +4 more
semanticscholar   +1 more source