Results 51 to 60 of about 1,730,968 (259)

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego, Kellee Parker, William C. Thomsen, James B. Ford, Mallorie B. Heneghan, David Spencer Mangum, Jennifer L. McNeer, Luke D. Maese, Claire E. F. Miller, Richard Lemons, Taumoha Ghosh   +10 more
wiley   +1 more source

Health effects of home energy efficiency interventions in England: a modelling study [PDF]

, 2015
Objective: To assess potential public health impacts of changes to indoor air quality and temperature due to energy efficiency retrofits in English dwellings to meet 2030 carbon reduction targets. Design: Health impact modelling study.
Chalabi, Z, Das, P, Davies, M, Hamilton, IG, Jones, B, Milner, J, Shrubsole, C, Wilkinson, P   +7 more
core   +2 more sources

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason, John P. Woodhouse, Joanna S. Yi, M. Monica Gramatges, Olga A. Taylor, Veronica A. Morales, Shalini Dhamodharan, Marley Roberts, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin L. Brown   +14 more
wiley   +1 more source

The consequences of delaying insulin initiation in UK type 2 diabetes patients failing oral hyperglycaemic agents: a modelling study [PDF]

, 2009
Background Recent data have shown that type 2 diabetes patients in the UK delay initiating insulin on average for over 11 years after first being prescribed an oral medication.
Gordon Goodall, Eric M Sarpong, Clarice Hayes, William J Valentine, American Diabetes Association, B Jonsson, R Williams, A Liebl, D Wanless, Y Ohkubo, The DCCT Research Group, The UK Prospective Diabetes Study Group, The UK Prospective Diabetes Study Group, The Diabetes Control and Complications Trial-Epidemiology of Diabetes Interventions and Complications Research Group, ML Lawson, IM Stratton, The ADVANCE Collaboration Group, E Selvin, American Diabetes Association, HC Gerstein, DM Nathan, DG Marrero, MJ Calvert, MJ Calvert, AJ Palmer, AJ Palmer, P Clarke, C Mathers, TO Tengs, National Institute for Clinical Excellence, RR Holman, H Yki-Jarvinen, MN Cook, A Rubino, LG Mellbin, K Malmberg, SL Bowker, LG Hemkens, U Smith, SH Saydah, GT Higgins, C Bebb, M Peyrot, A Phillips   +43 more
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Estimation of health state utilities in breast cancer

Patient Preference and Adherence, 2017
Seon-Ha Kim,1 Min-Woo Jo,2 Minsu Ock,2 Hyeon-Jeong Lee,2 Jong-Won Lee3,4 1Department of Nursing, College of Nursing, Dankook University, Cheonan, 2Department of Preventive Medicine, University of Ulsan College of Medicine, Seoul, 3Department of Breast ...
Kim SH, Jo MW, Ock M, Lee HJ, Lee JW
doaj  

Measurement of Quality of Life VI. Quality-Adjusted Life Years (QALY) is an Unfortunate Use of the Quality-of-Life Concept

The Scientific World Journal, 2003
The QALY (quality-adjusted life years) attempts to incorporate the dimension of quality of life into the evaluation by adjusting life years by a quality factor.
Soren Ventegodt, Joav Merrick, Niels Jorgen Andersen   +2 more
doaj   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

The impact of childhood RSV infection on children's and parents' quality of life: a prospective multicenter study in Spain

BMC Infectious Diseases, 2021
Background  Several immunisation candidates against RSV are in late-stage clinical trials. To evaluate the benefits of a potential vaccination programme, both economic and health benefits will be needed.
Eva Díez-Gandía, Carla Gómez-Álvarez, Mónica López-Lacort, Cintia Muñoz-Quiles, Isabel Úbeda-Sansano, Javier Díez-Domingo, Alejandro Orrico-Sánchez, Study collaborators   +7 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source