Results 71 to 80 of about 20,675,713 (257)

The Relationship between Urinary Incontinence Quality of Life and Sleep Quality in Women Over the Age of 60 Years

open access: yes, 2020
Aim: The study aimed to investigate the relationship between urinary incontinence quality of life and sleep quality in women over the age of 60 ...
Özlem Örsal   +5 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Economic evaluation of non-pharmacological interventions in Alzheimer's disease [PDF]

open access: yesDementia & Neuropsychologia
. Alzheimer's disease (AD) has significant physical, psychological, and socioeconomic impacts, shortens life expectancy, and reduces quality of life. Non-pharmacological interventions (NPIs) in dementia provide health gains.
Margarida Sobral, Susana Oliveira
doaj   +1 more source

Do quality-adjusted life years take account of lost income? Evidence from an Australian survey

open access: yes
Cost utility analysis, Outcomes, Quality-adjusted life years, Indirect benefits, Consumption benefits, I10, I18, I19,
Jeff Richardson   +2 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

The STAR trial protocol: a randomised multi-stage phase II/III study of Sunitinib comparing temporary cessation with allowing continuation, at the time of maximal radiological response, in the first-line treatment of locally advanced/metastatic Renal Cancer

open access: yesBMC Cancer, 2012
Background Over recent years a number of novel therapies have shown promise in advanced renal cell carcinoma (RCC). Internationally the standard of care of first-line therapy is sunitinib™, after a clear survival benefit was demonstrated over interferon ...
Collinson Fiona J   +13 more
doaj   +1 more source

Making Rasch decisions: the use of Rasch analysis in the construction of preference based health related quality of life instruments [PDF]

open access: yes
Objective: To set out the methodological process for using Rasch analysis alongside traditional psychometric methods in the development of a health state classification that is amenable to valuation.
Tsuchiya, A   +4 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Long-term cost-effectiveness of pharmacist-managed hypertension care in China

open access: yesBMC Health Services Research
Background Hypertension is one of the main causes of cardiovascular and kidney diseases in China. However, the rate of effective blood pressure control remains low.
Jingxuan Wei   +6 more
doaj   +1 more source

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