Results 111 to 120 of about 1,591,231 (284)

Cost-utility tele-stroke in adults with acute ischemic stroke. A systematic review

Public Health in Practice
Introduction: Tele-Stroke has been proposed as a solution to increase access to thrombolytic therapy in acute ischemic stroke. Objective: Synthesise the evidence of the cost-effectiveness of Tele-Stroke.
Luis Alberto López-Romero, Dora Inés Parra, Alexandra Cortés Aguilar, Fabio Alberto Camargo Figuera   +3 more
doaj   +1 more source

Economic evaluation of an extended nutritional intervention in older Australian hospitalized patients: a randomized controlled trial

BMC Geriatrics, 2018
Background Prevalence of malnutrition in older hospitalized patients is 30%. Malnutrition is associated with poor clinical outcomes in terms of high morbidity and mortality and is costly for hospitals.
Yogesh Sharma, Campbell Thompson, Michelle Miller, Rashmi Shahi, Paul Hakendorf, Chris Horwood, Billingsley Kaambwa   +6 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Cost–utility analysis of adapted problem adaptation therapy for depression in mild-to-moderate dementia caused by Alzheimer's disease: PATHFINDER randomised controlled trial

BJPsych Open
Background Depression is common in people with dementia, and negatively affects quality of life. Aims This paper aims to evaluate the cost-effectiveness of an intervention for depression in mild and moderate dementia caused by Alzheimer's disease over ...
Monica Panca, Robert Howard, Elizabeth Cort, Charlotte Rawlinson, Rebecca L. Gould, Martin Wiegand, Anne Marie Downey, Sube Banerjee, Chris Fox, Rowan Harwood, Gill Livingston, Esme Moniz-Cook, Gregor Russell, Alan Thomas, Philip Wilkinson, Nick Freemantle, Rachael Maree Hunter   +16 more
doaj   +1 more source

Oral splints for patients with temporomandibular disorders or bruxism: a systematic review and economic evaluation

Health Technology Assessment, 2020
Background: Splints are a non-invasive, reversible management option for temporomandibular disorders or bruxism. The clinical effectiveness and cost-effectiveness of splints remain uncertain.
Philip Riley, Anne-Marie Glenny, Helen V Worthington, Elisabet Jacobsen, Clare Robertson, Justin Durham, Stephen Davies, Helen Petersen, Dwayne Boyers   +8 more
doaj   +1 more source

Cost-utility of transcatheter aortic valve implantation for inoperable patients with severe aortic stenosis treated by medical management: a UK cost-utility analysis based on patient-level data from the ADVANCE study. [PDF]

, 2014
OBJECTIVE: To use patient-level data from the ADVANCE study to evaluate the cost-effectiveness of transcatheter aortic valve implantation (TAVI) compared to medical management (MM) in patients with severe aortic stenosis from the perspective of the UK ...
Bleiziffer, S, Bosmans, J, Brecker, S, Busca, R, Eaton, J, Gerckens, UJ, Linke, A, Mealing, S, Moat, N, Padhiar, A, Piazza, N, Sculpher, M, Tamburino, C, Wenaweser, P   +13 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Medical costs and quality-adjusted life years associated with smoking: a systematic review

BMC Public Health, 2016
Background Estimated medical costs (“T”) and QALYs (“Q”) associated with smoking are frequently used in cost-utility analyses of tobacco control interventions.
Shari P. Feirman, Allison M. Glasser, Lyubov Teplitskaya, David R. Holtgrave, David B. Abrams, Raymond S. Niaura, Andrea C. Villanti   +6 more
doaj   +1 more source

Putting the quality into quality-adjusted life years [PDF]

Journal of Public Health, 2003
Over recent decades, a great deal of effort has been devoted towards developing instruments that can be used to elicit health state values. All of these instruments are conceptually very different from one another and all suffer from serious inherent biases.
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source