Results 111 to 120 of about 21,139,354 (341)

The economic consequences of attention-deficit hyperactivity disorder in the Scottish prison system

BMC Psychiatry, 2018
Background Attention-deficit hyperactivity disorder (ADHD) is highly prevalent amongst prison inmates and the criminal justice system (CJS) likely bears considerable costs for offenders with ADHD.
Susan Young, Rafael A. González, Moshe Fridman, Paul Hodgkins, Keira Kim, Gisli H. Gudjonsson   +5 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

QALY losses for non-communicable diseases in Iranian adults: insights from a national cross-sectional study

Population Health Metrics
Background Non-communicable diseases (NCDs), constitute a major global public health challenge and represent the primary causes of mortality and morbidity worldwide. This study aims to estimate Quality-Adjusted Life Year (QALY) losses associated with six
Abdoreza Mousavi, Satar Rezaei, Ali Akbari Sari, Mohammad Amin Masoumi, Rajabali Daroudi   +4 more
doaj   +1 more source

Cost-Utility Analysis of Rosuvastatin (20 mg) to Prevent Cardiovascular Diseases in Iran

Advanced Biomedical Research
Background: Cardiovascular diseases are a main cause of disease burden in developing and developed countries. This study aimed to evaluate the cost-utility of rosuvastatin 20 mg in contrast with no intervention for the prevention of cardiovascular ...
Aziz Rezapour, Abdosaleh Jafari, Hamid Talebianpour   +2 more
doaj   +1 more source

Economic evaluation of an extended nutritional intervention in older Australian hospitalized patients: a randomized controlled trial

BMC Geriatrics, 2018
Background Prevalence of malnutrition in older hospitalized patients is 30%. Malnutrition is associated with poor clinical outcomes in terms of high morbidity and mortality and is costly for hospitals.
Yogesh Sharma, Campbell Thompson, Michelle Miller, Rashmi Shahi, Paul Hakendorf, Chris Horwood, Billingsley Kaambwa   +6 more
doaj   +1 more source

Prevalence and Losses in Quality-adjusted Life Years of Child Health Conditions: A Burden of Disease Analysis

Maternal and Child Health Journal, 2015
Objectives To estimate the prevalence and losses in quality-adjusted life years (QALYs) associated with 20 child health conditions. Methods Using data from the 2009–2010 National Survey of Children with Special Health Care Needs, preference weights were ...
Benjamin Matthew Craig, J. D. Hartman, Michelle A. Owens, Derek S. Brown   +3 more
semanticscholar   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Disability-adjusted life years (DALYs) based COVID-19 health impact assessment: A systematic review

, 2023
Background The emergence of COVID-19 has resulted in health, socio-economic, and political crises. The overall health impact of this disease can be measured by disability-adjusted life years (DALYs) which is the sum of the life years lost due to ...
Islam, Md Shahidul, Wark, Stuart, Gebeyehu, Daniel Teshome, East, Leah, Md Shahidul Islam, Leah East, Daniel Teshome Gebeyehu, Stuart Wark   +7 more
core   +1 more source

Oral splints for patients with temporomandibular disorders or bruxism: a systematic review and economic evaluation

Health Technology Assessment, 2020
Background: Splints are a non-invasive, reversible management option for temporomandibular disorders or bruxism. The clinical effectiveness and cost-effectiveness of splints remain uncertain.
Philip Riley, Anne-Marie Glenny, Helen V Worthington, Elisabet Jacobsen, Clare Robertson, Justin Durham, Stephen Davies, Helen Petersen, Dwayne Boyers   +8 more
doaj   +1 more source