Results 71 to 80 of about 1,728,317 (301)

Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy [PDF]

, 2017
Background: Chagas’ disease is an important cause of cardiomyopathy in Latin America. We aimed to compare clinical characteristics and outcomes in patients with heart failure (HF) with reduced ejection fraction caused by Chagas’ disease, with other ...
Claudio R. Gimpelewicz, Efraín A. Gómez, Felipe Martinez, Felix Ramires, Jean L. Rouleau, John J.V. McMurray, Karl Swedberg, Kenneth Dickstein, Lars Køber, Li Shen, Luis Eduardo Echeverría, Luiz Carlos Bodanese, Michael R. Zile, Milton Packer, null null, Pardeep S. Jhund, Scott D. Solomon, William T. Abraham   +17 more
core   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Cost-Utility Analysis of Colorectal Cancer Screening Starting at Age 45 Compared to Age 50 in Colombia

Revista Colombiana de Gastroenterología
Background: Colorectal cancer (CRC) is among the four cancers with the highest incidence and mortality in Colombia. CRC screening is currently recommended in national guidelines starting at age 50.
Gerardo Andrés Puentes Leal, Marcela Pérez Rodríguez , Esperanza Peña Torres   +2 more
doaj   +1 more source

A Decision Rule for Transplanting Non-Cadaveric Organs [PDF]

This paper conceptually analyzes the minimum probability of success required for transplanting non-cadaveric organs, its relationship with the initial, and possible rates of change in the, quality-adjusted life-years of the recipient and donor and its ...
Levy, Amnon
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Subjective Measures of Well-being [PDF]

well-being, objective, subjective, measurement, quality of life, worth, happiness adjusted life ...
Veenhoven, Ruut
core  

Decision-analytic cost-effectiveness model to compare prostate cryotherapy to androgen deprivation therapy for treatment of radiation recurrent prostate cancer [PDF]

, 2015
Objective: To determine the cost-effectiveness of salvage cryotherapy (SC) in men with radiation recurrent prostate cancer (RRPC). Design: Cost-utility analysis using decision analytic modelling by a Markov model.
Birrell, Fiona, Boyd, Kathleen A., Briggs, Andrew H., Jones, Rob J., Leung, Hing Y., Paul, Jim   +5 more
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Health economics evaluation of screening for sarcopenia among community-dwelling older persons

BMC Public Health
Objective Sarcopenia increased the risk of various adverse outcomes, including cardiovascular diseases, falls, and mortality. Implementing interventions could mitigate the harm caused by sarcopenia.
Yang Liu, Boran Sun, Jingyue Wang, Zhanliang Ruan, Yuan Wang, Jian Sun, Shu Wang, Wenli Lu   +7 more
doaj   +1 more source

Economic evaluation of non-pharmacological interventions in Alzheimer's disease [PDF]

Dementia & Neuropsychologia
. Alzheimer's disease (AD) has significant physical, psychological, and socioeconomic impacts, shortens life expectancy, and reduces quality of life. Non-pharmacological interventions (NPIs) in dementia provide health gains.
Margarida Sobral, Susana Oliveira
doaj   +1 more source