Results 81 to 90 of about 1,591,231 (284)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Impact of Inactivated Influenza Vaccination on Health‐Related Quality of Life Among Japanese Healthcare Workers

open access: yesImmunity, Inflammation and Disease
Background Influenza vaccinations are recommended for healthcare workers (HCWs). Quantification of the personal risks of vaccination compared to vaccine benefits can help guide more accurate benefit‐risk assessment and cost‐effectiveness analysis of ...
Taito Kitano, Sayaka Yoshida
doaj   +1 more source

Cost-Effectiveness of Strategies to Improve HIV Testing and Receipt of Results: Economic Analysis of a Randomized Controlled Trial [PDF]

open access: yes, 2010
The CDC recommends routine voluntary HIV testing of all patients 13-64 years of age. Despite this recommendation, HIV testing rates are low even among those at identifiable risk, and many patients do not return to receive their results.
Gillian D. Sanders   +46 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Cost-Utility Analysis of Colorectal Cancer Screening Starting at Age 45 Compared to Age 50 in Colombia

open access: yesRevista Colombiana de Gastroenterología
Background: Colorectal cancer (CRC) is among the four cancers with the highest incidence and mortality in Colombia. CRC screening is currently recommended in national guidelines starting at age 50.
Gerardo Andrés Puentes Leal   +2 more
doaj   +1 more source

A Decision Rule for Transplanting Non-Cadaveric Organs [PDF]

open access: yes
This paper conceptually analyzes the minimum probability of success required for transplanting non-cadaveric organs, its relationship with the initial, and possible rates of change in the, quality-adjusted life-years of the recipient and donor and its ...
Levy, Amnon
core  

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Economic evaluation of non-pharmacological interventions in Alzheimer's disease [PDF]

open access: yesDementia & Neuropsychologia
. Alzheimer's disease (AD) has significant physical, psychological, and socioeconomic impacts, shortens life expectancy, and reduces quality of life. Non-pharmacological interventions (NPIs) in dementia provide health gains.
Margarida Sobral, Susana Oliveira
doaj   +1 more source

Reverse-total shoulder arthroplasty cost-effectiveness: A quality-adjusted life years comparison with total hip arthroplasty.

open access: yesWorld Journal of Orthopaedics, 2016
AIM To compare reverse-total shoulder arthroplasty (RSA) cost-effectiveness with total hip arthroplasty cost-effectiveness. METHODS This study used a stochastic model and decision-making algorithm to compare the cost-effectiveness of RSA and total hip ...
Daniel Bachman, J. Nyland, R. Krupp
semanticscholar   +1 more source

Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy [PDF]

open access: yes, 2017
Background: Chagas’ disease is an important cause of cardiomyopathy in Latin America. We aimed to compare clinical characteristics and outcomes in patients with heart failure (HF) with reduced ejection fraction caused by Chagas’ disease, with other ...
Claudio R. Gimpelewicz   +17 more
core   +3 more sources

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