Results 51 to 60 of about 1,647,697 (336)

Laparoscopic versus open colorectal resection for cancer and polyps: A cost-effectiveness study [PDF]

open access: yes, 2014
Methods: Participants were recruited in 2006-2007 in a district general hospital in the south of England; those with a diagnosis of cancer or polyps were included in the analysis.
Dowson, H   +4 more
core   +1 more source

Fundamental Measurement: The Need Fulfilment Quality of Life (N-QOL) Measure

open access: yesINNOVATIONS in Pharmacy, 2021
The quality adjusted life year (QALY) has serious problems related to its failure to adhere to measurement theory. If a QALY is to be meaningful, the utility score that translates time spent to an equivalent time spent in so-called perfect health must ...
Paul C. Langley, Stephen P. McKenna
doaj   +1 more source

Cost-effectiveness of eplerenone in patients with systolic heart failure and mild symptoms [PDF]

open access: yes, 2014
Aim In the Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF), aldosterone blockade with eplerenone decreased mortality and hospitalisation in patients with mild symptoms (New York Heart Association class II ...
Akehurst, R.   +9 more
core   +3 more sources

Willingness to pay for one quality-adjusted life year in Iran [PDF]

open access: yesCost Effectiveness and Resource Allocation, 2019
Recent years have witnessed a strong tendency to apply economic evidence as a guide for making health resource allocation decisions, especially those related to reimbursement policies. One such measure is the use of the cost-effectiveness threshold as a benchmark.
Najmeh Moradi   +5 more
openaire   +4 more sources

Making Rasch decisions: The use of Rasch analysis in the construction of preference based health related quality of life instruments [PDF]

open access: yes, 2008
Objective: To set out the methodological process for using Rasch analysis alongside traditional psychometric methods in the development of a health state classification that is amenable to valuation.
Brazier, J.   +4 more
core   +2 more sources

Utility Weights for Allergic Rhinitis Based on a Community Survey with a Time Trade-off Technique in Japan

open access: yesAllergology International, 2009
Background: Allergic rhinitis is not a fatal disease, but its symptoms deteriorate the quality of life. High morbidity raises a concern about its impact on health care resources.
Kazuhiro Tamayama   +3 more
doaj   +1 more source

An Adaptive Management Model for Brown Bears in Hokkaido: Based on Total Population and the Number of Nuisance Bears

open access: yesPopulation Ecology, EarlyView.
Bear management changes management actions according to the horizontal axis of the population size and the vertical axis of the number of nuisance bears. Aiming for the target population size of Ntar, Actions I and II protect the bears, and Action IV reduces the population.
Hiroyuki Matsuda   +5 more
wiley   +1 more source

Measuring the impact of alcohol-related disorders on quality of life through general population preferences

open access: yesGaceta Sanitaria, 2017
Objective: To estimate the intangible effects of alcohol misuse on the drinker's quality of life, based on general population preferences Methods: The most important effects (dimensions) were identified by means of two focus groups conducted with ...
Eva Rodríguez-Míguez   +1 more
doaj   +1 more source

Productivity and quality-adjusted life years: QALYs, PALYs and beyond

open access: yes, 2023
We develop a unified framework for the measurement and valuation of health and productivity. Within this framework, we characterize evaluation functions allowing for compromises between the classical quality-adjusted life years (QALYs) and its polar productivity-adjusted life years (PALYs).
Schultz Hansen, Kristian   +2 more
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

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