Results 111 to 120 of about 19,026,882 (238)

Results of alternative strategies: costs, life expectancy, quality-adjusted life years (QALYs) gained.

, 2016
Results of alternative strategies: costs, life expectancy, quality-adjusted life years (QALYs) gained.
Pei Liu (93392), Hua Zhang (12549), Mingdong Huo (3092376), Jianqian Chao (146997)   +3 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Deriving monetary value of quality-adjusted life years through life extension from the value of a statistical life

Scientific Reports
To address the recent rise in healthcare expenditure due to an aging population, the rational allocation and efficient use of resources, based on scientific evidence, have become indispensable.
Yusuke Tanizawa, Kazuya Ito, Ryuta Takashima   +2 more
doaj   +1 more source

Live Long, Live Well: Quantifying the Health of Heterogenous Populations [PDF]

Various health-, quality-, and disability-adjusted life year or life expectancy (HALY, QALY, DALY; HALE, QALE, DALE) measures have become gold standards for defining outcomes in technology evaluation, population health monitoring, and other evaluative ...
John Mullahy
core  

Quality of life in polyneuropathy: association with biomarkers of small fiber impairment

, 2017
Background: Polyneuropathy presumably lowers quality of life (QoL). However, there is a lack of systematic studies that assess QoL changes and biomarkers of polyneuropathy as determinants of QoL.
謝松蒼;趙啟超, Lin, Meng-Ting;Lee, Lukas Jyuhn-Hsiarn;Chao, Chi-Chao;Hsieh, Sung-Tsang   +1 more
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Quality-Adjusted Life-Years lost for ambulatory ILI patients.

, 2014
Estimated average Quality-Adjusted Life-Years lost as a function of having an underlying illness and age, separately for ambulatory ILI respondents categorized as ‘likely flu’ or ‘unlikely flu’.
Philippe Beutels (43663), Samuel Coenen (397250), Joke Bilcke (262673)   +2 more
core   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Quality of life and quality-adjusted life years after stroke in Sierra Leone

International Journal of Stroke
Background: Stroke is a leading cause of mortality and negatively affects health-related quality of life (HRQoL). HRQoL after stroke is understudied in Africa and there are no reports of quality-adjusted life years after stroke (QALYs) in African countries.
Daniel Youkee, Gibrilla F Deen, Catherine Sackley, Durodami R Lisk, Iain Marshall, Marina Soley-Bori   +5 more
openaire   +3 more sources