Results 91 to 100 of about 20,468,877 (258)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Medical costs and quality-adjusted life years associated with smoking: a systematic review

BMC Public Health, 2016
Background Estimated medical costs (“T”) and QALYs (“Q”) associated with smoking are frequently used in cost-utility analyses of tobacco control interventions.
Shari P. Feirman, Allison M. Glasser, Lyubov Teplitskaya, David R. Holtgrave, David B. Abrams, Raymond S. Niaura, Andrea C. Villanti   +6 more
doaj   +1 more source

Cost-utility model input parameters: Principal event probabilities, lifetime costs and quality-adjusted life years.

Cost-utility model input parameters: Principal event probabilities, lifetime costs and quality-adjusted life years.
Dyfrig Hughes (40543), Bernd Duller (3834748), Elke Naujokat (18358266), Huw Lloyd Williams (18495674), Emily Holmes (418302), Christian P. Subbe (18495677)   +5 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Cost-utility tele-stroke in adults with acute ischemic stroke. A systematic review

Public Health in Practice
Introduction: Tele-Stroke has been proposed as a solution to increase access to thrombolytic therapy in acute ischemic stroke. Objective: Synthesise the evidence of the cost-effectiveness of Tele-Stroke.
Luis Alberto López-Romero, Dora Inés Parra, Alexandra Cortés Aguilar, Fabio Alberto Camargo Figuera   +3 more
doaj   +1 more source

Racial Disparities in Quality-Adjusted Life-Years Associated With Diabetes and Visual Impairment [PDF]

, 2012
OBJECTIVE Compare differences in health-related quality of life among blacks and whites to examine if race, diabetes, and visual impairment (VI) present a triple disadvantage in terms of quality-adjusted life expectancy. RESEARCH DESIGN AND METHODS Data
Fernandez, Cristina A., Arheart, Kristopher L., Galor, Anat, ARHEART, Kristopher L, Lam, Byron L., FERNANDEZ, Cristina A, LAM, Byron L, Zheng, D. Diane, Lee, David J., Muennig, Peter A., DIANE ZHENG, D, MUENNIG, Peter, McCollister, Kathryn E., LEE, David J, MCCOLLISTER, Kathryn E, Ocasio, Manuel   +15 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Trial‐based economic evaluation of mindfulness‐based cognitive therapy compared to treatment as usual for bipolar disorder

International Journal of Methods in Psychiatric Research
Objective Aim of this study was to assess the cost‐effectiveness and cost‐utility of mindfulness‐based cognitive therapy (MBCT) and treatment as usual (TAU) compared to TAU alone in adults with Bipolar disorder (BD). Methods An economic evaluation with a
Ben Wijnen, Maud Jansen, Annelieke vanVelthoven, Imke Hanssen, Marloes Huijbers, Silvia Evers, Anne Speckens   +6 more
doaj   +1 more source

Cost–utility analysis of adapted problem adaptation therapy for depression in mild-to-moderate dementia caused by Alzheimer's disease: PATHFINDER randomised controlled trial

BJPsych Open
Background Depression is common in people with dementia, and negatively affects quality of life. Aims This paper aims to evaluate the cost-effectiveness of an intervention for depression in mild and moderate dementia caused by Alzheimer's disease over ...
Monica Panca, Robert Howard, Elizabeth Cort, Charlotte Rawlinson, Rebecca L. Gould, Martin Wiegand, Anne Marie Downey, Sube Banerjee, Chris Fox, Rowan Harwood, Gill Livingston, Esme Moniz-Cook, Gregor Russell, Alan Thomas, Philip Wilkinson, Nick Freemantle, Rachael Maree Hunter   +16 more
doaj   +1 more source

A Good Life in Later Years: A Co-Produced Research Project [PDF]

, 2017
The ‘A Good Life Project’ evolved as a co-production study looking at quality of life in later years. Funded by the Life Changes Trust, and in partnership with Age Scotland, researchers from the University of Stirling worked hand in hand with
Gibson, Grant, Robertson, Jane, Greasley-Adams, Corinne, McCall, Vikki   +3 more
core