Background: Splints are a non-invasive, reversible management option for temporomandibular disorders or bruxism. The clinical effectiveness and cost-effectiveness of splints remain uncertain.
Philip Riley +8 more
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Medical costs and quality-adjusted life years associated with smoking: a systematic review
Background Estimated medical costs (“T”) and QALYs (“Q”) associated with smoking are frequently used in cost-utility analyses of tobacco control interventions.
Shari P. Feirman +6 more
doaj +1 more source
What can local authorities do to improve the social care-related quality of life of older adults living at home? Evidence from the Adult Social Care Survey [PDF]
Local authorities spend considerable resources on social care at home for older adults. Given the expected growth in the population of older adults and budget cuts on local government, it is important to find efficient ways of maintaining and improving ...
van der Horst, H.E. +16 more
core +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Cost-utility tele-stroke in adults with acute ischemic stroke. A systematic review
Introduction: Tele-Stroke has been proposed as a solution to increase access to thrombolytic therapy in acute ischemic stroke. Objective: Synthesise the evidence of the cost-effectiveness of Tele-Stroke.
Luis Alberto López-Romero +3 more
doaj +1 more source
Quality of Life Lost Due to Non-Fatal Road Crashes [PDF]
The objective of this paper is to evaluate the effect of a nonfatal road crash on the health-related quality of life of injured people. A new approach is suggested, based on the cardinalization of categorical Self-Assessed Health valuations.
Cubí-Mollá Patricia, Herrero Carmen
core
Smoking and health-related quality of life in English general population: Implications for economic evaluations [PDF]
Copyright @ 2012 Vogl et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution ...
Reiner Leidl +20 more
core +2 more sources
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Objective Aim of this study was to assess the cost‐effectiveness and cost‐utility of mindfulness‐based cognitive therapy (MBCT) and treatment as usual (TAU) compared to TAU alone in adults with Bipolar disorder (BD). Methods An economic evaluation with a
Ben Wijnen +6 more
doaj +1 more source

