Results 11 to 20 of about 2,407,609 (308)
Process knowledge discovery tools in compliance with Quality by Design concept. [PDF]
Farmacja Polska, 2019 The significant change in the pharmaceutical quality approach (QbD concept, PAT strategy) and focusing on improving the quality of drug products by reducing variability in the manufacturing process force the use of effective tools to discover knowledge ...
Joanna Ronowicz
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Heliyon, 2023 The present work deals with QbD-based development of FEB-loaded nanoemulsion (FEB-NE) in order to enhance bioavailability and permeability. In the beginning, the risk assessment was performed on different experimental variables using the Ishikawa diagram
Vishal C. Gurumukhi +5 more
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QbD approach to HPLC method development and validation of ceftriaxone sodium
Future Journal of Pharmaceutical Sciences, 2021 Background Quality by design (QbD) refers to the achievement of certain predictable quality with desired and predetermined specifications. A quality-by-design approach to method development can potentially lead to a more robust/rugged method due to ...
Krunal Y. Patel +3 more
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Implementing greening into design in analytical chemistry
Talanta Open, 2022 From the pharmaceutical industry is known the approach Quality-by-Design (QbD) and this has great influence on analytical methods and procedures it employs.
Jelena Jurjeva, Mihkel Koel
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Pharmaceuticals, 2022 A novel chaotropic chromatography method for the quantitative determination of bupropion and its impurities, following analytical quality-by-design (AQbD) principles, is presented.
Kostas Gkountanas +2 more
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Разработка и регистрация лекарственных средств, 2020 Introduction. Quality, along with efficacy and safety, are the key characteristics of a drug. Therefore, it is important in frame of pharmaceutical development to lay the foundation for obtaining a quality product and achieving the desired product ...
A. N. Golubev +3 more
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Reconciling Quality by Design and Transdermal Product Development
Pharmaceutics, 2020 Since my first exposure to the acronym ‘QbD’ more than ten years ago, I have been trying to understand exactly what QbD is and how I might incorporate its teachings into my twenty-odd years of experience developing transdermal systems. I feel
Kenneth Miller
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Understanding Pharmaceutical Quality by Design [PDF]
The AAPS Journal, 2014 This review further clarifies the concept of pharmaceutical quality by design (QbD) and describes its objectives. QbD elements include the following: (1) a quality target product profile (QTPP) that identifies the critical quality attributes (CQAs) of the drug product; (2) product design and understanding including identification of critical material ...
Amidon, Gregory +6 more
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Separations, 2022 A multicomponent pharmaceutical that contains loratadine, paracetamol, and pseudoephedrine was quantified using HPLC-PDA. The three analytes were well-separated and quantified in the dosage form on a C-18 column using a gradient mobile phase.
Naser F. Al-Tannak +3 more
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HPLC method development for fampridine using Analytical Quality by Design approach
Acta Pharmaceutica, 2020 Offering a systematic and multivariate analysis of the analytical procedure, development and validation of HPLC methods using Quality by Design approach are in the limelight of current research trends.
Kovács Béla +6 more
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