Results 21 to 30 of about 65,133,632 (292)

Quality by Design Approach for a Multicomponent Quantification Using HPLC-PDA and HPLC-MS: Application to Dosage Form and Biological Body Fluids

Separations, 2022
A multicomponent pharmaceutical that contains loratadine, paracetamol, and pseudoephedrine was quantified using HPLC-PDA. The three analytes were well-separated and quantified in the dosage form on a C-18 column using a gradient mobile phase.
Naser F. Al-Tannak, Bashayer J. Al-Shatti, Abdullah S. Al Ali, A. Hemdan   +3 more
doaj   +1 more source

Database Design for Quality [PDF]

, 1996
The approach employed to define a formal design methodology fot the development of easy to use, flexible, efficient and correct database systems is described.
Castelli D, Locuratolo E
openaire   +3 more sources

Quality-by-design-based development of ultradeformable nanovesiculartransgelosome of standardized Piper longum extract for melanoma - supplementary data

, 2023
Background: Melanoma is the most aggressive and deadly form of skin cancer. The stratum corneum of the skin is a major obstacle to dermal and transdermal drug delivery.
Dulla Naveen Kumar (16703779), Singh Shreya (16703780), Ashish Kumar Agrawal (16703784), Debadatta Mohapatra (11449636), Dhananjay Panigrahi (16703782), Alakh N Sahu (16703785)   +5 more
core   +1 more source

HPLC method development for fampridine using Analytical Quality by Design approach

Acta Pharmaceutica, 2020
Offering a systematic and multivariate analysis of the analytical procedure, development and validation of HPLC methods using Quality by Design approach are in the limelight of current research trends.
Kovács Béla, Boda Francisc, Fülöp Ibolya, Székely-Szentmiklósi István, Kelemen Éva Katalin, Kovács-Deák Boglárka, Székely-Szentmiklósi Blanka   +6 more
doaj   +1 more source

Quality by Design Approach for Development and Characterization of Granisetron Hydrochloride-Loaded Orodispersible Films

Pharmaceutical Fronts, 2023
Granisetron hydrochloride can be used to prevent and treat nausea and vomiting induced by chemotherapy. Its prolonged half-life and reduced dose requirement improve patient acceptance. However, patients undergoing chemotherapy often suffer from dysphagia
Ming-Yan Li, Bing Wang, Jun-Qi Zhang, Liu-Liu Yang, Jun-Tao He, Fang Chen   +5 more
doaj   +1 more source

Quality and safety by design [PDF]

Quality in Health Care, 2006
Rather than continuing to try to measure the width and depths of the quality chasm, a legitimate question is how does one actually begin to close the quality chasm? One way to think about the problem is as a design challenge rather than as a quality improvement challenge.
openaire   +2 more sources

Analytical quality-by-design approach for development and validation of HPLC method for the simultaneous estimation of omarigliptin, metformin, and ezetimibe: application to human plasma and dosage forms

BMC Chemistry, 2023
A simple, selective, and sensitive RP-HPLC method was proposed for the simultaneous determination of two co-administered antidiabetic drugs (omarigliptin and metformin) with an anti-hyperlipidemic drug (ezetimibe) in a medicinally-recommended ratio of 2 ...
Galal Magdy, Amira A. Al-enna, Fathalla Belal, Ramadan A. El-Domany, Ahmed M. Abdel-Megied   +4 more
doaj   +1 more source

Formulation Approaches for Improving the Dissolution Behavior and Bioavailability of Tolvaptan Using SMEDDS

Pharmaceutics, 2022
Tolvaptan, a selective vasopressin receptor antagonist, is a Class IV agent of Biopharmaceutical Classification System (BCS). To improve bioavailability after oral administration, the new tolvaptan-loaded self-microemulsifying drug delivery system ...
Jong-Hwa Lee, Gye-Won Lee
doaj   +1 more source

Scenario-Based Evaluation of Perception of Picture Quality Failures in LCD Televisions [PDF]

, 2009
Organised by: Cranfield UniversityIn innovative Consumer Electronics products, such as LCD televisions, consumers often perceive the product's malfunctioning differently than designers do. To support critical design decisions, it is therefore important
Scholten, L., Lu, Y., den Ouden, E., Keijzers, J.   +3 more
core   +6 more sources

Development of a robust and reliable reverse-phase high-performance liquid chromatography (RP-HPLC) method using analytical quality by design principles for the accurate determination of esculin in its bulk form

Future Journal of Pharmaceutical Sciences, 2023
Background Analytical quality by design is a proactive, holistic, and data-driven approach to quality that emphasizes risk assessment and management. This can lead to more robust and reliable methods than traditional approaches.
Sarvesh Patil, Anjana Adhyapak, Priya Shetti, Rohan Gurao   +3 more
doaj   +1 more source