Results 21 to 30 of about 2,583,795 (262)
HPLC method development for fampridine using Analytical Quality by Design approach
Acta Pharmaceutica, 2020 Offering a systematic and multivariate analysis of the analytical procedure, development and validation of HPLC methods using Quality by Design approach are in the limelight of current research trends.
Kovács Béla +6 more
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Pharmaceutical Fronts, 2023 Granisetron hydrochloride can be used to prevent and treat nausea and vomiting induced by chemotherapy. Its prolonged half-life and reduced dose requirement improve patient acceptance. However, patients undergoing chemotherapy often suffer from dysphagia
Ming-Yan Li +5 more
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Future Journal of Pharmaceutical Sciences, 2023 Background Analytical quality by design is a proactive, holistic, and data-driven approach to quality that emphasizes risk assessment and management. This can lead to more robust and reliable methods than traditional approaches.
Sarvesh Patil +3 more
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Pharmaceutics, 2022 Tolvaptan, a selective vasopressin receptor antagonist, is a Class IV agent of Biopharmaceutical Classification System (BCS). To improve bioavailability after oral administration, the new tolvaptan-loaded self-microemulsifying drug delivery system ...
Jong-Hwa Lee, Gye-Won Lee
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Evaluation of formulation variables on azithromycin nanoparticles prepared by emulsification solvent diffusion method using quality by design approach [PDF]
Pharmaceutical Sciences Asia, 2022 The study aims to investigate the effect of formulation variables on the characteristics of azithromycin (AZI) nanoparticles using a quality by design approach. AZI nanoparticles were prepared by the emulsification solvent diffusion method.
Nguyen-Thach Tung +2 more
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Designing-in of quality through axiomatic design [PDF]
IEEE Transactions on Reliability, 1995 Decisions made during the design stage of product and process development profoundly affect product quality and process productivity. To aid in design decision making, a theoretical framework is advanced; the axiomatic approach to design. Axiomatic design consists of: (1) domains in the design world; (2) mapping between these domains; (3 ...
openaire +2 more sources
Molecules, 2019 The development of pharmaceutical nanoformulations has accelerated over the past decade. However, the nano-sized drug carriers continue to meet substantial regulatory and clinical translation challenges.
Michele Herneisey +5 more
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BMC Chemistry, 2023 For the simultaneous estimation of two co-formulated antihistaminic drugs (Bilastine and Montelukast), a novel and eco-friendly reversed-phase HPLC approach with both diode array and fluorescence detection modes was designed.
Aya Roshdy +4 more
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Chinese Medicine, 2019 Background Quality by design (QbD) is an advanced drug quality control concept that has been gradually implemented in the optimization of manufacturing processes of Chinese medicines.
Jingjing Pan +6 more
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QbD Based Media Development for the Production of Fab Fragments in E. coli
Bioengineering, 2019 Ranibizumab is a biotherapeutic Fab fragment used for the treatment of age-related macular degeneration and macular oedema. It is currently expressed in the gram-negative bacterium, Escherichia coli.
Deepak Kumar +3 more
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