Results 11 to 20 of about 7,649,748 (300)

Quality by Design for the Nanoformulation of Cosmeceuticals [PDF]

Pharmaceutics
Cosmeceuticals are cosmetic formulations that are intended to alleviate skin conditions that affect its appearance and functionality. They are not considered medications but contain molecules that exert biological action on the skin beyond traditional ...
Gerardo Leyva-Gómez, Elizabeth Piñón-Segundo, Zaida Urban-Morlan, Nancy E. Magaña-Vergara, David Quintanar-Guerrero, Betzabeth Jaime-Escalante, Néstor Mendoza-Muñoz   +6 more
doaj   +2 more sources

Aspects and Implementation of Pharmaceutical Quality by Design from Conceptual Frameworks to Industrial Applications [PDF]

Pharmaceutics
Background/Objectives: Quality by Design (QbD) has revolutionized pharmaceutical development by transitioning from reactive quality testing to proactive, science-driven methodologies.
Shiwei Yang, Xingming Hu, Jinmiao Zhu, Bin Zheng, Wenjie Bi, Xiaohong Wang, Jialing Wu, Zimeng Mi, Yifei Wu   +8 more
doaj   +2 more sources

Quality by Design and In Silico Approach in SNEDDS Development: A Comprehensive Formulation Framework [PDF]

Pharmaceutics
Background/Objectives: The Self-Nanoemulsifying Drug Delivery System (SNEDDS) has been widely applied in oral drug delivery, particularly for poorly water-soluble compounds.
Sani Ega Priani, Taufik Muhammad Fakih, Gofarana Wilar, Anis Yohana Chaerunisaa, Iyan Sopyan   +4 more
doaj   +2 more sources

Optimization of Microfluidizer-Produced PLGA Nano-Micelles for Enhanced Stability and Antioxidant Efficacy: A Quality by Design Approach [PDF]

Pharmaceutics
Introduction: In this study, we aimed to optimize the microfluidizer-based preparation of poly(lactic-co-glycolic acid) nano-micelles (PLGANM), increasingly used for parenteral delivery of poorly water-soluble drugs but typically exhibiting poor physical
Esma Nur Develi Arslanhan, Fatemeh Bahadori, Zahra Eskandari, Muhammed Zahid Kasapoglu, Erkan Mankan   +4 more
doaj   +2 more sources

Determination of Bupropion and Its Impurities via a Chaotropic Chromatography Method Following Analytical Quality-by-Design Principles for Method Development

Pharmaceuticals, 2022
A novel chaotropic chromatography method for the quantitative determination of bupropion and its impurities, following analytical quality-by-design (AQbD) principles, is presented.
Kostas Gkountanas, Anđelija Malenović, Yannis Dotsikas   +2 more
doaj   +1 more source

A Quality By Design Approach For Longitudinal Quality Attributes [PDF]

Journal of Biopharmaceutical Statistics, 2015
The concept of quality by design (QbD) as published in ICH-Q8 is currently one of the most recurrent topics in the pharmaceutical literature. This guideline recommends the use of information and prior knowledge gathered during pharmaceutical development studies to provide a scientific rationale for the manufacturing process of a product and provide ...
Lebrun, Pierre, Giacoletti, Katherine, Scherder, Tara, Rozet, Eric, Boulanger, Bruno   +4 more
openaire   +3 more sources

Tablets Development Based on Clover Meadow Grass Phytosubstance Using Design of the Experiment Method and QdD Tools

Разработка и регистрация лекарственных средств, 2020
Introduction. Quality, along with efficacy and safety, are the key characteristics of a drug. Therefore, it is important in frame of pharmaceutical development to lay the foundation for obtaining a quality product and achieving the desired product ...
A. N. Golubev, Th. I. Nguen, V. V. Sorokin, I. E. Kauhova   +3 more
doaj   +1 more source

Reconciling Quality by Design and Transdermal Product Development

Pharmaceutics, 2020
Since my first exposure to the acronym ‘QbD’ more than ten years ago, I have been trying to understand exactly what QbD is and how I might incorporate its teachings into my twenty-odd years of experience developing transdermal systems. I feel
Kenneth Miller
doaj   +1 more source

Quality engineering of a traction alternator by robust design [PDF]

, 2010
Robust design is an engineering methodology for improving productivity during research and development so that high-quality products can be developed and produced quickly and at low cost. A large electrical company was developing traction alternators for
E V Gijo, Hunter J. S., J Antony, Kackar R. N., Lucas J. M., Myers R. H., Myers R. H., Phadke M. S., Rao C. R., Taguchi G., Taguchi G., Taguchi G., U H Acharya, Welch W. J., Wu C. F. J.   +14 more
core   +1 more source

Quality by Design Approach for a Multicomponent Quantification Using HPLC-PDA and HPLC-MS: Application to Dosage Form and Biological Body Fluids

Separations, 2022
A multicomponent pharmaceutical that contains loratadine, paracetamol, and pseudoephedrine was quantified using HPLC-PDA. The three analytes were well-separated and quantified in the dosage form on a C-18 column using a gradient mobile phase.
Naser F. Al-Tannak, Bashayer J. Al-Shatti, Abdullah S. Al Ali, A. Hemdan   +3 more
doaj   +1 more source