Results 241 to 250 of about 7,524,867 (293)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Commercialization of the Xalkori Pediatric Multiparticulate Product Using Quality-by-Design Principles. [PDF]

Pharmaceutics
Bartlett J, Culver N, Zhang X, Waybrant B, Sullivan H, Howell L.   +5 more
europepmc   +1 more source

Implementation of Established Conditions and Use of Quality by Design Principles during Drug Development: Status in the US, EU, and Japan. Data from a Survey Conducted by the Japan Pharmaceutical Manufacturers Association (JPMA). [PDF]

Ther Innov Regul Sci
Nakayama Y, Yamauchi S, Shimizume K, Nakanishi A, Masuyama M, Ozaki Y, Nakamura K, Fujikawa M, Kobayashi M, Kashitani Y.   +9 more
europepmc   +1 more source

Quality by design for mRNA platform purification based on continuous oligo-dT chromatography. [PDF]

Mol Ther Nucleic Acids
Qu J, Nair A, Muir GW, Loveday KA, Yang Z, Nourafkan E, Welbourne EN, Maamra M, Dickman MJ, Kis Z.   +9 more
europepmc   +1 more source

Quality-by-design-engineered mitochondrial targeted nanoparticles for glioblastoma therapy. [PDF]

RSC Adv
Dahifale A, Agnihotri TG, Jain A, Jain A.   +3 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Quality by Design

Asian Journal of Research in Pharmaceutical Science, 2016
Quality by design (QbD) is an essential part of the modern advance to pharmaceutical quality. QbD is best key to build a quality in all pharmaceutical products. Under this concepts of be throughout design and growth of product, it is important to identify desire product performance report [Target product profile (TPP), Quality Target product profile ...
Sushila D. Chavan, Nayana V. Pimpodkar, Amruta S. Kadam, Puja S. Gaikwad   +3 more
openaire   +2 more sources

Quality by design for biopharmaceuticals

Nature Biotechnology, 2009
The US Food and Drug Administration's 'quality by design' approach is likely to transform the manufacture of biologics.
Anurag S, Rathore, Helen, Winkle
openaire   +2 more sources

Quality by Design

The TQM Magazine, 1990
Reveals how Nestle builds quality and safety into its products. Describes how the company employs a strict methodology to safeguard the quality and safety of its products. Reports on the Hazard Analysis Critical Control Point concept. Concludes that the final product still has to be checked because of government regulations.
openaire   +1 more source