Results 141 to 150 of about 815,060 (335)

Sparse Attention-driven Quality Prediction for Production Process Optimization in Digital Twins [PDF]

open access: yesarXiv
In the process industry, long-term and efficient optimization of production lines requires real-time monitoring and analysis of operational states to fine-tune production line parameters. However, complexity in operational logic and intricate coupling of production process parameters make it difficult to develop an accurate mathematical model for the ...
arxiv  

Influence of controlled field traffic on soil quality indicators [PDF]

open access: yesEngineering for Rural Development, 2018
Stanislav Kovar   +3 more
openaire   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Quality control plans and performance indicators for highway bridges across Europe

open access: yes, 2016
In Europe, there is a large disparity from country to country regarding the way performance indicators are quantified and goals specified. The main objective of COST Action TU-1406 is to establish quality specifications for roadway bridges based on reliable and widely accepted performance indicators that could be accepted on a European basis.
openaire   +2 more sources

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Optimal Management in the Operation of Complex Technical Systems

open access: yesЖурнал інженерних наук
Developing a cost management system for a complex technical system (CTS) at the stages of its life cycle is a modern trend aimed at creating sustainable cooperation ties based on requirements, including those of manufacturers and consumers.
Dyadyura K.   +4 more
doaj   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

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