Results 131 to 140 of about 6,574,159 (309)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

IMPROVEMENT MANAGEMENT OF TEACHER RESOURCE AMONG VOCATIONAL HIGH SCHOOL BASED ON INTERNATIONAL STANDARD SCHOOL INVEST (INDONESIA VOCATIONAL EDUCATION STRENGTHENING) IN YOGYAKARTA [PDF]

open access: yes, 2012
This education research aimed to: (1) find an overview of resource about teacher’s resource improvement management in vocational high school based on international INVEST in Yogyakarta, (2) find the effectiveness for the implementation of quality ...
Dian Rustamana Indra Putra, Dian Rustamana Indra Putra
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Report on objective ride quality evaluation [PDF]

open access: yes
The correlation of absorbed power as an objective ride measure to the subjective evaluation for the bus data was investigated. For some individual bus rides the correlations were poor, but when a sufficient number of rides was used to give reasonable ...
Park, W. H., Wambold, J. C.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Green and Efficient Extraction of Phenolic Components from Plants with Supramolecular Solvents: Experimental and Theoretical Studies

open access: yesMolecules
The supramolecular solvent (SUPRAS) has garnered significant attention as an innovative, efficient, and environmentally friendly solvent for the effective extraction and separation of bioactive compounds from natural resources.
Bo-Hou Xia   +6 more
doaj   +1 more source

Comparative Performance Evaluation: Quality [PDF]

open access: yes, 2014
Fichera, E.   +2 more
openaire   +1 more source

Evaluating the Improvement of Quality of Life in Rural Areas [PDF]

open access: yes
The research starts from the necessity to create specific tools for evaluating the impacts of rural development policies on fragile areas. The study is motivated by the need for developing an appropriate evaluation method that leads to gather meaningful ...
Cagliero, Roberto   +3 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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