Results 171 to 180 of about 2,456,901 (316)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Resilient Agrifood System Science Group: Evaluation Report [PDF]

open access: yes
The CGIAR 2030 Research and Innovation Strategy sets priorities to deliver solutions for development through 33 initiatives across three interlinked action areas: Systems Transformation, Resilient Agrifood Systems (RAFS), and Genetic Innovation. The RAFS
Fakoya, K.   +4 more
core  

Quality Evaluation and Multi-Criteria Optimization of Cookies Fortified with Lyophilized Black Goji. [PDF]

open access: yesFoods
Šavikin K   +7 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Quality evaluation level decision in outsourcing under asymmetric information

open access: yes, 2006
In this paper, the issue of quality evaluation level decision problem in outsourcing is studied under different information backgrounds. Based on the quality contracting optimization models of Stanley and others, a principal agent model concerned with ...
Zhang CH(张翠华)   +2 more
core  

Evaluation and Quality of Care Issues

open access: yes
peer reviewedThis chapter presents the recent developments in defining and evaluating the quality of children's palliative care. The large variety of medical conditions, ages, care settings and pathways for children in palliative care makes it difficult ...
Coombes, Lucy, FRIEDEL, Marie
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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