Results 151 to 160 of about 7,175,511 (297)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Accessible, All-Polymer Metasurfaces: Low Effort, High Quality Factor. [PDF]

ACS Nano
Hirler M, Antonov AA, Baù E, Aigner A, Heimig C, Hu H, Tittl A.   +6 more
europepmc   +1 more source

High Quality Factor in Solution-Processed Inorganic Microcavities Embedding CsPbBr₃ Perovskite Nanocrystals. [PDF]

ACS Appl Opt Mater, 2023
Bertucci S, Escher A, Cirignano M, De Franco M, Locardi F, Patrini M, Comoretto D, Lova P, Di Stasio F.   +8 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

High quality-factor terahertz phonon-polaritons in layered lead iodide. [PDF]

Nat Commun
Santos CN, Feres FH, Hannotte T, Peretti R, Vanwolleghem M, Eliet S, Walter B, Faucher M, Cernescu A, Freitas RO, Lampin JF.   +10 more
europepmc   +1 more source

Quality Factor Improvement of a Thin-Film Piezoelectric-on-Silicon Resonator Using a Radial Alternating Material Phononic Crystal. [PDF]

Micromachines (Basel), 2023
Zhu C, Su M, Workie TB, Tang P, Ye C, Bao JF.   +5 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Topological edge state cavities: simultaneous enhancement of quality factor and free spectral range. [PDF]

Light Sci Appl
Ding S, Wang Z, Lu C.
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Textured Lead-Free Ceramic with High Thermal Stability and Electrical Quality Factor. [PDF]

Small
Nanda A, Karan SK, Kunwar S, Yan Y, Fanton M, Priya S, Lanagan M, Poudel B.   +7 more
europepmc   +1 more source