Results 111 to 120 of about 10,211,998 (304)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Evaluation of the efficacy of peer-learning method in nutrition students of Shiraz University of Medical Sciences

open access: yesJournal of Advances in Medical Education and Professionalism, 2014
Introduction: One of notable initiatives in improving the academic education is to use the abilities of students to learn together in a new and effective system of peer learning.
MOHAMMAD REZA DEHGHANI   +3 more
doaj  

Pueraria thomsonii Benth.: a high-biomass plant for cadmium phytoremediation with high accumulation in stems

open access: yesFrontiers in Plant Science
Heavy metal contamination in farmland soils threatens food security and human health. Phytoremediation provides a sustainable strategy, with Pueraria thomsonii emerging as a promising candidate due to its high-biomass production.
Xing Li   +10 more
doaj   +1 more source

A guide to synthesising qualitative research for researchers undertaking health technology assessments and systematic reviews [PDF]

open access: yes, 2011
This report highlights the key methods for qualitative synthesis and raises points of discussion and debate within the ...
Ritchie, Karen   +3 more
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Non-spore-forming thermoduric bacteria vary considerably in thermal resistance in milk media between strains from the same genus

open access: yesJournal of Dairy Science
: Thermoduric bacteria, defined as those that survive temperatures considerably above their maximum growth temperature, are enumerated in milk using the laboratory pasteurization count (LPC) test.
Caroline Motzer   +2 more
doaj   +1 more source

Report of the review of the application of the Framework for Improving Quality in our Health services

open access: yes, 2018
In 2016, the HSE National Quality Improvement Division (QID) published Part One of the Framework for Improving Quality in our Health Service (henceforth referred to as the “Framework”). The Framework was developed as a response to a need to orientate the
National Quality Improvement Team
core  

Evaluation of an evidence based quality improvement innovation for patients with musculoskeletal low back pain in an accident and emergency setting

open access: yes, 2015
We conducted a five stage pilot study which initially consisted of a review of 75 case notes of people attending an emergency department (ED) in an inner London Teaching Hospital with musculoskeletal (MSK) low back pain (LBP).
Rantell, K   +3 more
core   +1 more source

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