Results 161 to 170 of about 1,848,071 (313)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A Multi-Country Community of Practice to Strengthen Quality Improvement in Low- and Middle-Income Countries: A Quality Improvement Program Description. [PDF]

Healthcare (Basel)
Bhargava S, Haq HA, Franklin BA, Davis E, Anabwani-Richter F, Bhembe T, Dlamini LP, Dlamini M, Chapola A, Kafumba N, Zinyemba CM, Bvumbwe M, Jjuuko KR, Kanywa JB, Kiragga D, Isaac AB, Makhalanyane E, Nyembo L, Mahlaha R, Farirai JT, Ketang'enyi EW, Imsen AEM, Costas I, Torrey SB.   +23 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Valuing water quality improvement in China : a case study of lake Puzhehei in Yunnan province [PDF]

While polluted surface water is encountered across most of China, few economic valuation studies have been conducted on water quality changes. Limited information about the economic values associated with those potential water quality improvements or ...
Shi, Yuyan, Kamata, Takuya, Kim, Yoonhee, Wang, Hua   +3 more
core  

Clinical audit and quality improvement: rivals, partners, or one and the same? [PDF]

Front Health Serv
Davey N, Shearer H, Matthew D, Smyth J, Meddick-Dyson SA.   +4 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Reducing Transfusions in Neuromuscular Spinal Fusion: A National Surgical Quality Improvement Program-Pediatrics Quality Improvement Project. [PDF]

J Pediatr Soc North Am
Archer H, Pinto VL, Russell F, Briceño V, Ard M, Hensch L, Teruya J, Daugherty TG, Molchen W, Coleman RD, Hanson D, Gerow FT, Montgomery NI.   +12 more
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Reflections on a global partnership for perinatal quality improvement in Rwanda. [PDF]

BMJ Paediatr Open
Tuyisenge L, Habonimana JP, Nsengiyumva A, Cyiza FR, Manzi E, Desie S, Pledge A, McMurtrie S, Muzard-Banes C, Bontoux M, Taylor S.   +10 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source