Results 111 to 120 of about 7,863,465 (307)

Quality indicators

Biochemia medica, 2009
Načelo cjelovitog pristupa upravljanju kvalitetom podrazumijeva specifičan ustroj laboratorija koji teži pružati usluge i proizvode u potpunosti zadovoljavajući potrebe svojih korisnika: bolesnika i kliničkog osoblja. Jedna od ključnih postavki cjelovitog pristupa upravljanju kvalitetom je svakako i neprekidno poboljšavanje temeljem pokazatelje koji ...
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Temporally Correlated Deep Learning-Based Horizontal Wind-Speed Prediction

Sensors
Wind speed affects aviation performance, clean energy production, and other applications. By accurately predicting wind speed, operational delays and accidents can be avoided, while the efficiency of wind energy production can also be increased.
Lintong Li, Jose Escribano-Macias, Mingwei Zhang, Shenghao Fu, Mingyang Huang, Xiangmin Yang, Tianyu Zhao, Yuxiang Feng, Mireille Elhajj, Arnab Majumdar, Panagiotis Angeloudis, Washington Ochieng   +11 more
doaj   +1 more source

AIR QUALITY IN THE CITY OF TG JIU [PDF]

Fiabilitate şi Durabilitate, 2014
One of the most important problems of the modern age is the air pollution. Within this work I realized a description of Tgjiu City: geographic location, climate, hydrographical network, variations in temperature, terrain, sources of pollution.
Adina TĂTAR
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Development of quality indicators for physiotherapy care

Fysioterapeuten, 2017
Quality indicators are indirect measures of quality within an area. The development of quality indicators is based on transparent and systematic methods where professional as well as value-based considerations are combined.
Anne Christie, Hanne Dagfinrud
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source