Results 141 to 150 of about 12,119,388 (349)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Prescription of paracetamol-containing medications as indicator of quality of prescribing [PDF]
, 2007 Batty, Gwenno M. +6 more
core +1 more source
Comparative analysis of the quality of European institutions 2003-2009: convergence or divergence? [PDF]
, 2009 This paper gives a comparative cross-country analysis of the quality of the institutional framework that underpins economic governance in European countries. The paper attempts to identify the trends of change in the quality of institutions and determine
Cuckovic, Nevenka, Jurlin, Kresimir
core +1 more source
Oman Medical Journal, 2011 Objective: To evaluate the knowledge, attitude and practice (KAP) of physicians towards the Electronic Medical Record (EMR) system.Methods: A cross-sectional survey including physicians from various clinical specialties was conducted.
Anuradha Ganesh +3 more
doaj
Frontiers in NutritionIntroductionRaw laver (Pyropia spp.) quality assessment is largely subjective and lacks scientific standardization.MethodsThis study established objective quality markers by integrating biochemical profiling with market-based valuation.
Seul-Ki Park +8 more
doaj +1 more source
Early mortality after chemotherapy as a quality indicator-the leukemia perspective. [PDF]
Blood Cancer J, 2023 Kantarjian H, Welch MA, Sasaki K.
europepmc +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source