Results 61 to 70 of about 687,925 (260)

Involving patients in quality indicator development – a systematic review

, 2013
Thomas Kötter,1,2 Friederike Anna Schaefer,2 Martin Scherer,2 Eva Blozik1,2 1Institute for Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany; 2Department of Primary Medical Care, University Medical Center Hamburg ...
Kötter T, Scherer M, Schaefer FA, Blozik E   +3 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Development of a quality indicator set to measure and improve quality of ICU care for patients with traumatic brain injury.

, 2019
BACKGROUND: We aimed to develop a set of quality indicators for patients with traumatic brain injury (TBI) in intensive care units (ICUs) across Europe and to explore barriers and facilitators for implementation of these quality indicators.
Suzanne Polinder, Badenes, R., van den Bergh, Walter M., Takala, Riikka, de Keizer, Nicolette F., Jacobs, Bram, Payen, Jean-Francois, Depreitere, B., Lingsma, Hester F., Verhofstad, M.H.J., Steyerberg, E.W., Jacobs B., Jellema, Korne, Payen J. -F., Chieregato, A., Van Den Bergh W. M., Coburn, M., Chieregato A., Flaatten, H., Delphi panel, Huijben, Jilske, Maas, Andrew I.R., Valeinis, E., Jellema, K., Coburn, Mark, Haitsma, Iain, Lecky F., Citerio, G., Valeinis E., Oldenbeuving, A.W., Helbok, Raimund, Stocchetti, N., Steyerberg, Ewout W., Lingsma, H.F., Van Der Jagt M., Koskinen, Lars-Owe D.,, de Keizer, NF, Flaatten, Hans, Wilson, Lindsay, Nicolette F. de Keizer, Steiner, L.A., Bilotta, Federico, Maas, A.I.R., Lecky, Fiona, Moller K., van der Jagt, Mathieu, Schoonman G. G., Steiner L. A., de Keizer, Nicolette, Schoonman, G.G., Delgado, Maria Cruz Martin, Menon, D.K. (David ), Taccone, Fabio Silvio, Jacobs, B., Cnossen M. C., Grauwmeijer, Erik, Vos, Pieter E., Huijben, A.L.C.J.R.M. (Jilske), Oldenbeuving A. W., Maegele, M., Menon, D, Keizer, N.F., Koskinen L. -O. D., Menon, D., Grauwmeijer, E., Martin Delgado, Maria Cruz, Polinder, Suzanne, Taccone F. S., Wilson L., van Essen, Thomas, Lingsma H. F., Badenes, Rafael, Maas, Andrew, Cnossen, Maryse, Ercole, A., Maegele, Marc, Jagt, M.D., Stocchetti N., Citerio, Giuseppe, Ewout W. Steyerberg, De Keizer N. F., Delargy M., Steyerberg E. W., Cingolani E., Delgado, M.C.M., Cnossen, M.C., Ribbbers, G.M., Koskinen, Lars-Owe D., Maas, AIR, Helbok R., Moreno R., Oldenbeuving, Annemarie W., de Keizer, N.F., Van Essen T., Cnossen, M., Hoedemaekers, Cornelia, Golyk V., Ercole A., Polinder, S., Cnossen, MC, Pejakovic, Jasmina, Stocchetti, Nino, Vos P. E., Nelson, D., Jellema K., Beishuizen, Albertus, Ribbbers, Gerard M., van Leeuwen, Nikki, Grauwmeijer E., Vos, PE, Huijben, Jilske A., Verhofstad M. H. J., Cingolani, E., Aries, M., Verhofstad, Michael H.J., Lindsay Wilson, Maas A. I. R., Hoedemaekers C., Menon, David, the Delphi panel, Maas, A.I., Tenovuo, Olli, Eveline J. A. Wiegers, Van Leeuwen N., Verhofstad, Michiel, Hoedemaekers, C., Haitsma I., Moller, Kirsten, Maas, Andrew I. R., Nelson D., Ercole, Ari, Koskinen, L.O.D., David Menon, Giuseppe Citerio, Essen, T. van, Delargy, Mark, Flaatten H., Ribbers, Gerard, Takala R., Moreno, R., Rossaint, R., Tenovuo O., Coles J. P., Bilotta, F., Helbok, R., Aries M., Fiona Lecky, Badenes R., Verhofstad, Michiel; id_orcid, Depreitere B., Silvio, Fabio, Andrew I. R. Maas, Ari Ercole, Lecky, F., Golyk, Volodymyr, Tenovuo, O., Valeinis, Eglis, Delphi panel,, Ribbers, Gerard; id_orcid, Maryse C. Cnossen, Ribbbers G. M., Ercole, A, Beishuizen, A., Wilson, L., Huijben, J.A., Wiegers, Eveline J.A., Møller, Kirsten, Wiegers, Eveline J. A., Keizer, N.F. (Nicolette) de, Huijben J. A., Vos, P.E., Silvio, F., Haitsma, I., Verhofstad, Michael H. J., Bilotta F., Pejakovic, J., Coburn M., Leeuwen, N. van, Citerio G., Depreitere, Bart, Moller, K., Maas, A. (Arne), Delargy, M., Golyk, V., Schoonman, Guus Geurt, Lingsma, Hester, Jagt, M. van der, Nelson, David, Jilske A. Huijben, Wiegers, E.J.A., Mathieu van der Jagt, Steiner, Luzius A., Menon D., Beishuizen A., Steyerberg, Ewout, Coles, J.P., Payen, J.F., Wiegers E. J. A., Cnossen, Maryse C., Keizer, N.F. de, Bergh, W.M. van den, Rossaint R., Hester F. Lingsma, Polinder S., Rossaint, Rolf, Wiegers, Eveline, Chieregato, Arturo, Coles, Jonathan P., Maegele M., Takala, R., Pejakovic J., Cingolani, Emiliano, Aries, Marcel, Moreno, Rui, van der Jagt, M., Delgado M. C. M.   +215 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Article Quality Indicator: Proposing a New Indicator for Measuring Article Quality in Scopus and Web of Science [PDF]

, 2019
For different aims in science policy, careful analysis of the academic articles and their quality and quantity based on acceptable criteria seems indispensable.
Ghazavi, Roghayeh, Ashrafi-rizi, Hasan, Taheri, Behjat   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Investigation of Electromagnetic Gauges for Determining In-Place HMA Density, 2007 [PDF]

, 2007
Density is an important component of hot-mix asphalt (HMA) pavement quality and long-term performance. Insufficient density of an in-place HMA pavement is the most frequently cited construction-related performance problem.

core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source