Results 61 to 70 of about 2,148,940 (313)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Searching for non-English literature may be unnecessary for German HTA Reports [version 3; peer review: 2 approved, 2 approved with reservations, 1 not approved]

open access: yesF1000Research
Background Health technology assessment (HTA) reports are based on comprehensive information retrieval. Current standards discourage the use of search restrictions, such as publication date and language.
Stefan Sauerland   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A birth cohort study in the Middle East: the Qatari birth cohort study (QBiC) phase I

open access: yesBMC Public Health, 2017
Background The latest scientific reports raise concerns about the rapidly increasing burden of chronic diseases in the state of Qatar. Pregnant Qatari women often confront complications during pregnancy including gestational diabetes, hypertension ...
Eman Sadoun   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Searching for non-English literature may be unnecessary for German HTA Reports [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved]

open access: yesF1000Research
Background Health technology assessment (HTA) reports are based on comprehensive information retrieval. Current standards discourage the use of search restrictions, such as publication date and language.
Stefan Sauerland   +5 more
doaj   +1 more source

Case-crossover study to examine the change in postpartum risk of pulmonary embolism over time

open access: yesBMC Pregnancy and Childbirth, 2017
Background Although the current guidelines recommend anticoagulation up until 6 weeks after delivery in women at high risk of venous thromboembolism (VTE), the risk of VTE may extend beyond 6 weeks.
Grégoire Ficheur   +7 more
doaj   +1 more source

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