Results 71 to 80 of about 2,678,403 (260)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Quality of Care and Job Satisfaction in the European Home Care Setting: Research Protocol

, 2016
Introduction: Since the European population is ageing, a growing number of elderly will need home care. Consequently, high quality home care for the elderly remains an important challenge.
Van Eenoo, Liza, Liza Van Eenoo, Henriëtte van der Roest, Anja Declercq, van der Roest, Henriette, Declercq, Anja, Hein van Hout, van Hout, Hein   +7 more
core   +1 more source

Systems for the management of respiratory disease in primary care - an international series: United Kingdom [PDF]

, 2010
INTRODUCTION: The UK National Health Service (NHS) is essentially publicly funded through general taxation. Challenges facing the NHS include the rise in prevalence of long-term conditions and financial pressures.
Allison Worth, Mark Levy, Worth, Allison, Levy, Mark L., Fletcher, Monica, Pinnock, Hilary, Aziz Sheikh, Monica Fletcher, Hilary Pinnock, Pinnock, Hilary; id_orcid, Hoskins, Gaylor, Levy, Mark, Gaylor Hoskins, Sheikh, Aziz, Levy, Mark L   +14 more
core   +1 more source

The DMP atlas for North Rhine-Westphalia, Germany: results of the disease management programmes on district level

Research in Health Services & Regions
Disease Management Programmes (DMP) in Germany were initiated to enhance the quality of ambulatory health care for specific chronic diseases. They aim to prevent the progression of the disease and comorbidity as well as to improve quality of life.
Sabine Groos, Jens Kretschmann, Arne Weber, Michaela Assheuer, Bernd Hagen   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Quality of Care Program; Legislative report to the General Assembly

, 2003
Annual, Oct. 2005-; Semiannual, Mar. 2004-Oct. 2004; Annual, Mar. 2003; Mar. 2003-; Title from cover.; This report was initiated with the creation of Connecticut's Quality of Care Program.; Latest issue consulted: Oct. 2007; Report date changed from Mar.

core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Patient-Centred Care: Improving Quality and Safety by Focusing Care on Patients and Consumers

, 2011
Patient-centred care is health care that is respectful of, and responsive to, the preferences, needs and values of patients and consumers. The widely accepted dimensions of patient-centred care are respect, emotional support, physical comfort ...
Dunbar, Nicola, Luxford, Karen, Poole, Naomi, Piper, Donella   +3 more
core  

Development and validation of an index to assess hospital quality management systems. [PDF]

, 2014
Objective: The aim of this study was to develop and validate an index to assess the implementation of quality management systems (QMSs) in European countries. Design: Questionnaire development was facilitated through expert opinion, literature review and
Kristensen, S, Pfaff, Holger, Ommen, O, Pfaff, H, Chow, A, Bottaro, S., Wang, A., Lívio, A., Suñol, R., Shaw, C., Plochg, T, Kristensen, S., Depaigne-Loth, A., Depaigne-Loth, A, Kutaj-Wasikowska, H, Kus, H, Secanell, M., Klazinga, N.S., Mannion, Russell, Ozturk, K., Bruneau, Charles, Leite, I, Botje, D, Kutryba, B, Groene, Oliver, Saillour-Glenisson, F, Garel, Pascal, Almeman, F., Lívio, A, Eiras, M, Wang, A, Kutryba, Barbara, Arah, O.A., Franca, M, Saluvan, M, Hammer, A., Almeman, F, Bartels, Paul, Jones, S., Kringos, DS, Secanell, M, Wagner, C., Groene, O., Garel, P, Dersarkissian, Maral, Groene, O, Thompson, C.A., Kutaj-Wąsikowska, Halina, Leite, I., Arah, OA, Lopez, MA, Botje, Daan, Suñol Sala, Rosa, Wagner, C, Kus, H., Vlcek, Frantisek, Franca, M., DerSarkissian, M., Escoval, Ana, Jones, S, Thompson, A, Car, M., Lombarts, M.J.M.H., Escoval, A, Eiras, M., Klazinga, NS, Klazinga, N., Wagner, Cordula, Bartels, P, Plochg, Thomas, Chow, A., Shaw, C, Dersarkissian, M, Klazinga, N, Kringos, Dionne, Klaus, E, Bruneau, C, Arah, Onyebuchi A., Vallejo, P., Thompson, A., Lombarts, MJMH, Car, M, Vlcek, F, Ommen, O., Saluvan, M., Thompson, CA, Klaus, E., Bottaro, S, Suñol, R, Saillour-Glenisson, F., Vallejo, P, Lopez, M. A., Mannion, R, Michel, P, Ozturk, K, Hammer, A, Michel, P.   +96 more
core   +1 more source