Results 61 to 70 of about 2,678,403 (260)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Is patient-centredness in European hospitals related to existing quality improvement strategies? Analysis of a cross-sectional survey (MARQuIS study). [PDF]

, 2009
BACKGROUND: There is growing recognition of patients' contributions to setting objectives for their own care, improving health outcomes and evaluating care.
Lombarts, MJMH, Klazinga, N., Groene, O., Groene, O, Thompson, A, Lombarts, M.J.M.H., Lombarts, M. J. M. H., Klazinga, N, Suñol, R, Suñol, R., Groene, Oliver, Suñol Sala, Rosa, Alonso, J., Alonso, J, Thompson, A.   +14 more
core   +1 more source

The searchbuildR shiny app: A new implementation of the objective approach for search strategy development in systematic reviews

Cochrane Evidence Synthesis and Methods
Introduction One of the main tasks in information retrieval is the development of Boolean search strategies for systematic searches in bibliographic databases. This includes the identification of free‐text terms and controlled vocabulary.
Claudia Kapp, Naomi Fujita‐Rohwerder, Jona Lilienthal, Wiebke Sieben, Siw Waffenschmidt, Elke Hausner   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A prospective cluster randomized trial of an interventions bundle to reduce inappropriate antibiotic use for upper respiratory tract infections in the outpatient setting

BMC Infectious Diseases
Background Antibiotic overuse and increasing antimicrobial resistance are global public health threats. We determined the impact of a multicomponent intervention in reducing inappropriate antibiotic use for upper respiratory tract infections (URTIs) in ...
Adeel A. Butt, Sherin Shams, Atika Jabeen, Asma Ali Al-Nuaimi, Jeyaram Illiayaraja Krishnan, Aimon B. Malik, Samah Saleem, Maryam Hassan Abdulaziz, Naheel Ismail Seyam, Kamran Aziz, Dalia Kandil, Anil G. Thomas, Hanaa Nafady-Hego, Muzna I. Lone, Jameela Al Ajmi, Zain A. Bhutta, Noora AlSulaiti, Wael E. Said Hussein, Sandy Semaan, Samya Ahmad Al-Abdulla, Mohamed Ghaith Al-Kuwari, Abdul-Badi Abou-Samra   +21 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Exploration of support workers and volunteers initiation of advance care planning and quality of life conversations in palliative care. [PDF]

, 2018
Treetops Hospice Care, in partnership with University of Derby are commencing a research project exploring the outcomes of developing support workers and volunteers, in initiating conversations around quality of life.
Hembrow, Alison, Watson, Sharan
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Quality Assurance Policies and Indicators for Long-Term Care in the European Union, Country Report: Austria. ENEPRI Research Report No. 105, February 2012 [PDF]

, 2012
In Austria, the responsibilities for long-term care mainly lie with the provinces, although federal and organisational-level initiative has grown. Quality assurance policies focus overwhelmingly on the health system and are only slowly appearing in the ...
Kalmar, Marcel, Kraus, Markus, Czypionka, Thomas   +2 more
core