Results 151 to 160 of about 5,181,801 (356)

Laser Cutting of Stainless Steel Thin Sheets with Pulsed Nd:Yag Laser [PDF]

open access: yes, 2008
The parameters of laser cutting mainly depend on material and from thickness. In case of a given material and thickness many settings can be chosen. In this article we examine the laser cutting of 0,4 mm thickness stainless steel sheets with pulsed Nd ...
Dobránszky, János   +2 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Focusing on Project Metrics [PDF]

open access: yes, 2008
{Excerpt} The need to ensurethat scarce fundingis applied to effective projects is a goal shared by all. Focusing on common parameters of project performance is a means to that end.
Serrat, Olivier
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Assessment of Avifauna and Water Quality Parameters of Mangla Wetland, Azad Kashmir, Pakistan [PDF]

open access: diamond, 2020
Muhammad Umar   +4 more
openalex   +1 more source

Investigating the shortcomings of HMM synthesis [PDF]

open access: yes, 2013
This paper presents the beginnings of a framework for formal testing of the causes of the current limited quality of HMM (Hidden Markov Model) speech synthesis.
King, Simon, Merritt, Thomas
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Application of LANDSAT to the surveillance and control of lake eutrophication in the Great Lakes basin [PDF]

open access: yes
The author has identified the following significant results. Computer techniques were developed for mapping water quality parameters from LANDSAT data, using surface samples collected in an ongoing survey of water quality in Saginaw Bay.
Rogers, R. H.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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