Results 71 to 80 of about 860,910 (266)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Relationship among Quality Transformation, Quality Requirements and Quality Dimensions of services in Hospitals under Supervision of Medical Sciences Universities and Presenting Model

open access: yesJournal of Health Sciences and Surveillance System, 2016
Background: According to quality transformation of services during the time, the quality requirements and standards also change and recognition of these requirements and transformation process can assist in recognizing the quality dimensions of services.
Zahra Bahrami Nejad   +2 more
doaj  

Production of scandium radionuclides for theranostic applications: towards standardization of quality requirements. [PDF]

open access: yesEJNMMI Radiopharm Chem, 2021
Mikolajczak R   +6 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

RECENT MARKET REQUIREMENTS FOR PORK QUALITY IN GERMANY [PDF]

open access: yesPoljoprivreda, 2007
Meat market is changing continuously. The amount of meat sold in butcher shops is decreasing while pre packed meat in grocery stores and discounters is growing up to more than 50 % of the total consumption in 2007 (forecast).
E. Kallweit, Martina Henning, U. Baulain
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

What Is Quality? A Management Discipline and the Translation Industry Get Acquainted

open access: yesRevista Tradumàtica, 2014
One way to answer the question “What is translation quality?” is to start with a framework put forward by Garvin (1984). That framework describes five approaches to determining quality: Transcendent, Product-Based, User-Based, Production-Based ...
Paul Fields   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy