Results 61 to 70 of about 2,852,414 (315)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Risk maps for evaluation of water-quality monitoring requirements in England & Wales [PDF]

, 2020
This report details the steps taken in the process of producing risk (hazard) maps for chemical parameters listed in the European Commission Directive 98/83/EC on the quality of water intended for human consumption and the national Water Supply (Water ...
Bearcock, J.M., Marchant, B.P., Smedley, P.L., Cartwright, C.E., Cave, M.R., Milne, C.J.   +5 more
core  

A cross-disciplinary toolkit to assess the risk of faecal indicator loss from grassland farm systems to surface waters. [PDF]

, 2009
Diffuse microbial pollution from agriculture is a key contributor to water quality impairment. Reducing the risk of microbial contamination of watercourses from agricultural sources requires both environmentally appropriate and socially acceptable ...
Oliver, D. M., Fish, R, Fish, R. D., Hodgson, Chris J, Chadwick, David R., Heathwaite, A.L., Chadwick, D. R., Chadwick, Dave R, Hodgson, C. J., Fish, Rob, Hodgson, C.J., Hodgson, Chris J., Oliver, David, Oliver, David M., Winter, Michael, Heathwaite, A. L., Heathwaite, A Louise, Winter, M., Heathwaite, A. Louise, Oliver, D.M., Chadwick, D.R.   +20 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Reproductive Toxicity of Mequindox in a Two-Generation Study in Wistar Rats

Frontiers in Pharmacology, 2018
Mequindox (MEQ), belonging to quinoxaline-di-N-oxides (QdNOs), has been extensively used as a synthetic antibacterial agent. To evaluate the reproductive toxicity of MEQ, different concentrations of MEQ were administered to Wistar rats by feeding diets ...
Qianying Liu, Zhixin Lei, Qin Wu, Ihsan Awais, Muhammad A. B. Shabbir, Saeed Ahmed, Zainab Fatima, Xu Wang, Yuanhu Pan, Shuyu Xie, Zonghui Yuan, Zonghui Yuan, Zonghui Yuan   +12 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A risk-based approach to course quality assurance

, 2010
A decade ago, Queensland University of Technology (QUT) developed an innovative annual Courses\ud Performance Report, but through incremental change, this report became quite labour-intensive.
Nielsen, Samuel, Towers, Stephen J., McLean, S. Vianne, Alderman, Lyn   +3 more
core  

Quality of life and risk of malnutrition in a home-dwelling population over 75 years old

, 2016
Objectives: To evaluate the quality of life of a noninstitutionalized population aged older than 75 y by determining nutritional and health status, and to investigate the relationship between nutritional risk and quality of life.
Goñi Cambrodón, Isabel, Hernandez-Galiot, Ana   +1 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source