Results 1 to 10 of about 12,856,576 (256)
Quality by Design: Development of the Quality Target Product Profile (QTPP) for Semisolid Topical Products [PDF]
Pharmaceutics, 2020 In recent years, the “quality by design” (QbD) approach has been used for developing pharmaceutical formulations. This is particularly important for complex dosage forms such as topical semisolid products.
Sarika Namjoshi +4 more
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Assessing the Appropriateness of Formulations on the WHO Model List of Essential Medicines for Children: Development of a Paediatric Quality Target Product Profile Tool [PDF]
Pharmaceutics, 2022 The World Health Organization’s Model List of Essential Medicines for Children (EMLc) presents a list of the most efficacious, safe, and cost-effective medicines for priority conditions, intended for use in children up to 12 years of age.
Jennifer Walsh +5 more
doaj +6 more sources
Edaravone for the Treatment of Motor Neurone Disease: A Critical Review of Approved and Alternative Formulations against a Proposed Quality Target Product Profile [PDF]
PharmaceuticsEdaravone is one of two main drugs for treating motor neurone disease (MND). This review proposes a specific quality target product profile (QTPP) for edaravone following an appraisal of the issues accounting for the poor clinical uptake of the approved ...
Riuna O’Neill +3 more
doaj +4 more sources
Pharmaceutics, 2023 The present article exemplifies the application of the concept of quality by design (QbD) for the systematic development of a nanoparticulate imiquimod (IMQ) emulsion gel formulation as an investigational medicinal product (IMP) for evaluation in an ...
Jonas Pielenhofer +12 more
doaj +3 more sources
Brazilian Journal of Pharmaceutical Sciences, 2022 The current investigation entail systematic Quality by Design (QbD)-enabled approach for the development of Sustained released embedded drug delivery systems of L-Arginine employing ionic gelation technique to attain improved patient compliance.
Vijay Sharma, Lalit Singh, Navneet Verma
doaj +1 more source
Разработка и регистрация лекарственных средств, 2022 Introduction. One of the modern remedies used to treat vaginal infections are suppositories "Depantol", which have an antiseptic, regenerating effect due to the combination of chlorhexidine and dexpanthenol.
I. E. Smekhova +4 more
doaj +1 more source
Soft Gelatine Capsules- Critical Quality Attributes of Chosen Excipients and Capsules Parameters Following the Quality by Design Concept [PDF]
Acta Poloniae Pharmaceutica, 2023 Soft gel capsules are a common form of medicine and food supplements. Quality, productivity and manufacturing time is crucial for producers during their development and industrial operations.
Barbara Owczarek +1 more
doaj +1 more source
AAPS Open, 2021 Skin cancer is fifth most diagnosed disease in human population due to ultraviolet radiation (UV) exposure. Gamma oryzanol (OZ) is a natural antioxidant, and it also has skin anti-aging properties. OZ is naturally found in rice bran oil.
Harsh S. Shah +6 more
doaj +1 more source
SN Applied Sciences, 2021 QbD approach empowers the pharma researchers to minimize the number of experimental trials and time. It helps identify the significant, influential factors such as critical material attributes, critical formulation variables, and critical process ...
Dhananjay Panigrahi +3 more
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Beni-Suef University Journal of Basic and Applied Sciences, 2022 Background The current study expands on the use of design of experiment in developing cefuroxime axetil mucoadhesive minitablets for treating antibiotic-associated colitis.
Jayanti Panda +4 more
doaj +1 more source