Results 71 to 80 of about 2,145,260 (311)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Avoidable food waste in the distribution sector: quantification and valorization

Journal of Agricultural Engineering
Significant food waste occurs during distribution due to inefficiencies in handling, storage, and logistics. This research investigates food waste in the distribution sector, focusing on quantification and valorization, through three systematic ...
Arianna Cusmai, Abhishek Dattu Narote, Alessio Tugnolo, Roberto Beghi, Valentina Giovenzana   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Pour une sociologie historique de la quantification

, 2008
La quantification est devenue un signe d’objectivité, de rigueur et d’impartialité mobilisée dans des situations très variées, depuis le débat politique jusqu’à la démonstration scientifique, en passant par les indicateurs d’entreprise ou la mesure de l ...
Alain Desrosières
core  

Quantifying Methane Emission Rates Using Downwind Measurements

Encyclopedia
This entry describes the methods used to quantify methane emissions from either point or area sources using downwind methods. The methods described could be used as a practical guide to quantify emissions of any trace gas type from either a point or area
Stuart N. Riddick
doaj   +1 more source

V/Q SPECT for the Assessment of Regional Lung Function: Generation of Normal Mean and Standard Deviation 3-D Maps

Frontiers in Medicine, 2020
Background: V/Q SPECT/CT is attractive for regional lung function assessment, but accurate delineation and quantification of functional lung volumes remains a challenge.
David Bourhis, David Bourhis, Philippe Robin, Philippe Robin, Marine Essayan, Ronan Abgral, Ronan Abgral, Solène Querellou, Cécile Tromeur, Cécile Tromeur, Pierre-Yves Salaun, Pierre-Yves Salaun, Pierre-Yves Le Roux, Pierre-Yves Le Roux   +13 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Heparinase treatment of heparin-contaminated plasma from coronary artery bypass grafting patients enables reliable quantification of microRNAs

, 2016
BackgroundmicroRNAs have recently been identified as powerful biomarkers of human disease. Reliable polymerase chain reaction (PCR)-based quantification of nucleic acids in clinical samples contaminated with polymerase inhibitor heparin requires ...
Kondratov, K, Popov, M, Kurapeev, D, Kostareva, A,, Fedorov, A, Minasian, S, Sidorova, M, Galagudza, M   +7 more
core   +1 more source

Emissions to Air in a Seaport – An Approach to Modelling, Quantification and Reduction

Promet (Zagreb)
Emission sources associated with port operations are very different and ports are obliged to develop adequate responses. After a general introduction, an overview on literature related to emissions to air in ports and summary of already implemented ...
Deda ĐELOVIĆ
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source