Results 81 to 90 of about 204,570 (278)

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

open access: yesAdvanced Science, EarlyView.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche   +21 more
wiley   +1 more source

Unified estimators of smooth quantile and quantile density functions

open access: yesJournal of Statistical Planning and Inference, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Cheng, Cheng, Parzen, Emanuel
openaire   +1 more source

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

open access: yesAdvanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu   +9 more
wiley   +1 more source

A new class of gamma distribution

open access: yesActa Scientiarum: Technology, 2017
This paper presents a new class of probability distributions generated from the gamma distribution. For the new class proposed, we present several statistical properties, such as the risk function, expansions to density and cumulative function, moment ...
Cícero Carlos Ramos de Brito   +3 more
doaj   +1 more source

Coincident Fluorescence‐Burst Analysis of Actin Cargo Molecules in Secreted Single Diffusing Extracellular Vesicles From Human Induced Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen   +4 more
wiley   +1 more source

Power Prior Elicitation in Bayesian Quantile Regression

open access: yesJournal of Probability and Statistics, 2011
We address a quantile dependent prior for Bayesian quantile regression. We extend the idea of the power prior distribution in Bayesian quantile regression by employing the likelihood function that is based on a location-scale mixture representation of ...
Rahim Alhamzawi, Keming Yu
doaj   +1 more source

Uniform Bias Study and Bahadur Representation for Local Polynomial Estimators of the Conditional Quantile Function [PDF]

open access: yes
This paper investigates the bias and the Bahadur representation of a local polynomial estimator of the conditional quantile function and its derivatives.
Camille Sabbah, Emmanuel Guerre
core  

Approximation of high quantiles from intermediate quantiles

open access: yes, 2016
Motivated by applications requiring quantile estimates for very small probabilities of exceedance, this article addresses estimation of high quantiles for probabilities bounded by powers of sample size with exponents below -1.
de Valk, Cees
core   +1 more source

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

open access: yesAdvanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li   +13 more
wiley   +1 more source

The Log-Expo Inverse Gompertz Distribution: properties and Estimations [PDF]

open access: yesMaǧallaẗ Al-Buḥūṯ Al-Mālīyyaẗ wa Al-Tiğāriyyaẗ
This paper introduces the Log-Expo Inverse Gompertz Distribution (LET-IG) three-parameter distribution and examines some of its mathematical properties. The study derives the density distribution, reliability function, and hazard rate function.
محمد عبد القادر   +1 more
doaj   +1 more source

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