Results 91 to 100 of about 27,716,395 (263)

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

New Techniques for Qualitative and Quantitative Analysis of Proteomes

, 2012
New Techniques for Qualitative and Quantitative Analysis of ...
张玉奎
core  

Mathematical model and stability of SWCNT- and MWCNT-based nanofluid flow with thermal and chemically reactive effects inside a porous vertical cone

Frontiers in Chemistry
This study investigates the significance of single-walled (SWCNTs) and multi-walled (MWCNTs) carbon nanotubes with a convectional fluid (water) over a vertical cone under the influences of chemical reaction, magnetic field, thermal radiation and ...
Haihua Xu, Fuad A. Awwad, Emad A. A. Ismail, Waris Khan   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Quantitative analysis of dependency structures Quantitative linguistics ;, v. 72./ edited by Jingyang Jiang, Haitao Liu.

, 2018
In English.Includes bibliographical references and indexes.The series Quantitative Linguistics publishes books on all aspects of quantitative methods and models in linguistics, text analysis and related research fields.
Jiang Jingyang, Liu Haitao
core  

Heuristic computational approach for nonlinear reaction–diffusion kinetics in catalytic systems

Scientific Reports
The Lane-Emden equations are essential tools for modeling heat and mass transfer, chemical reactions, and various scientific fields. This study focuses on solutions to Lane-Emden equations in chemical engineering.
Saad Jamshed, Muhammad Shoaib, Hijaz Ahmad, Fuad A. Awwad, Emad A. A. Ismail, Noman Yousaf   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Quantitative X-ray mapping, scatter diagrams and the generation of correction maps to obtain more information about your material

, 2014
Quantitative X-ray mapping with silicon drift detectors and multi-EDS detector systems have become an invaluable analysis technique and one of the most useful methods of X-ray microanalysis today. The time to perform an X-ray map has reduced considerably
Moran, Ken, Wuhrer, Richard (R17216)
core  

The emerging field of Robo Advisor: A relational analysis

Heliyon
Robo advising is an emerging business model that aims to popularize investment advisory services by automating all the activities involved. The robo-advisor (RA) stream of research is relatively new, yet it has started to attract the attention of ...
Mar Arenas-Parra, Héctor Rico-Pérez, Raquel Quiroga-Garcia   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source