Results 101 to 110 of about 27,716,395 (263)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Quantitative tools of strategic analysis
, 2011 The tools of strategic analysis have always played a significant role in strategic theory and, notably, in strategic analysis. Nevertheless, what is apparently missing in the literature is a classification or formalization that provides a ranking or ...
VERNIZZI, Silvia, SOLINAS, Giulia
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Entropy-Based Evidence Functions for Testing Dilation Order via Cumulative Entropies
EntropyThis paper introduces novel non-parametric entropy-based evidence functions and associated test statistics for assessing the dilation order of probability distributions constructed from cumulative residual entropy and cumulative entropy.
Mashael A. Alshehri
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
An Introduction to Quantitative Text Analysis for Linguistics
An Introduction to Quantitative Text Analysis for Linguistics: Reproducible Research Using R is a pragmatic textbook that equips students and researchers with the essential concepts and practical programming skills needed to conduct quantitative text ...
Francom, Jerid
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Finite Element Analysis of Aximsymmetric Geometries in Quantitative NDE [PDF]
, 1980 Solution of the inversion problem in quantitative eddy current NDE requires an adequate mathematical model to describe the complicated interactions of currents, fields and flaws in materials.
Palanisamy, R. +3 more
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Quantitative phase analysis of α-Fe impurity in Ce2Fe17 matrix from neutron powder diffraction data
, 1993 The multicomponent Rietveld profile refinement technique for powder neutron diffraction patterns has been applied to arrive at a quantitative phase analysis of crystalline Ce2Fe17 and α-Fe impurity in a powder specimen of ...
Yusuf, Sk. Mohammad
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A New Method for Quantitative Analysis of Cell Surface Glycoproteome
, 2012 A New Method for Quantitative Analysis of Cell Surface ...
叶明亮 +6 more
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