Results 81 to 90 of about 27,716,395 (263)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Supplemental_Appendix_B – Supplemental material for Quantitative Synthesis of Research Evidence: Multilevel Meta-Analysis

, 2018
Supplemental material, Supplemental_Appendix_B for Quantitative Synthesis of Research Evidence: Multilevel Meta-Analysis by Mariola Moeyaert in Behavioral ...
Mariola Moeyaert (5902586)
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Supplemental_Appendix_A – Supplemental material for Quantitative Synthesis of Research Evidence: Multilevel Meta-Analysis

, 2018
Supplemental material, Supplemental_Appendix_A for Quantitative Synthesis of Research Evidence: Multilevel Meta-Analysis by Mariola Moeyaert in Behavioral ...
Mariola Moeyaert (5902586)
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

R Code for Quantitative Analysis

, 2019
R Code supporting the quantitative analysis. Data called for by this code are in the "quantitative analysis" tab of the "GBLA_forDryad_datasets" excel ...
Baughman, Owen W., Agneray, Alison C., Forister, Matthew L., Fiegener, Rob, Kaye, Thomas N., Kilkenny, Francis F., St. Clair, John Bradley, Horning, Matthew E., Ott, Jeffery, Johnson, Richard C., Leger, Elizabeth A., Espeland, Erin K.   +11 more
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Reliability analysis of parallel systems with dependent components and Archimedean copulas

Journal of Inequalities and Applications
In this paper, preservation properties of reversed hazard rate order and a relative overall reversed hazard rate order under the structure of a parallel system with dependent components having lifetimes coupled by an Archimedean copula are established ...
Mashael A. Alshehri
doaj   +1 more source

From Whence Commeth Data Misreporting? A Survey of Benford’s Law and Digit Analysis in the Time of the COVID-19 Pandemic

Mathematics
We survey the literature on the use of Benford’s distribution digit analysis applied to COVID-19 case data reporting. We combine a bibliometric analysis of 32 articles with a survey of their content and findings.
Călin Vâlsan, Andreea-Ionela Puiu, Elena Druică   +2 more
doaj   +1 more source