Results 11 to 20 of about 320,184 (194)

Formal executable descriptions of biological systems [PDF]

, 2005
The similarities between systems of living entities and systems of concurrent processes may support biological experiments in silico. Process calculi offer a formal framework to describe biological systems, as well as to analyse their behaviour, both ...
Brodo, Linda, Curti, Michele, Degano, Pierpaolo, Prandi, Davide, Priami, Corrado, Quaglia, Paola   +5 more
core   +1 more source

Biological Networks [PDF]

, 2019
Networks of coordinated interactions among biological entities govern a myriad of biological functions that span a wide range of both length and time scales—from ecosystems to individual cells and from years to milliseconds.
Neda Bagheri (Ed.), Rudiyanto Gunawan (Ed.)   +1 more
core   +1 more source

Detection of regulator genes and eQTLs in gene networks

, 2016
Genetic differences between individuals associated to quantitative phenotypic traits, including disease states, are usually found in non-coding genomic regions.
A Butte, A Chatr-Aryamontri, A Clauset, A Joshi, A Joshi, A Kundaje, AA Shabalin, AJ Enright, AJ Walhout, AS Dimas, B Schwanhausser, B Zhang, B Zhang, C Cenik, CO Daub, D Koller, DA Cusanovich, DM Greenawalt, E Bonnet, E Ravasz, E Segal, EC Neto, EC Neto, EC Neto, EE Schadt, EE Schadt, EE Schadt, EE Schadt, EE Schadt, EJ Foss, F Grubert, F Yue, FA Cubillos, FW Albert, G Hemani, G Nicholson, GD Smith, GH Golub, H Foroughi Asl, H Talukdar, HN Kadarmideen, J Millstein, J Qi, J Zhu, J Zhu, J Zhu, JE Aten, JF Ayroles, JJ Faith, JL Björkegren, JS Liu, K Basso, K Qu, KG Ardlie, L Wu, LA Hindorff, LH Hartwell, LS Chen, M Ashburner, M Civelek, M Georges, M Gerstein, M Medvedovic, M Schmidt, M Scutari, MA Schaub, MB Eisen, MD Ritchie, ME Goddard, MEJ Newman, MEJ Newman, MV Rockman, MV Rockman, N Friedman, N Friedman, N Friedman, N Laird, O Stegle, P Langfelder, P Langfelder, P Langfelder, P Lu, R Sharan, R Sharan, RB Brem, RW Williams, S Lee, S Roy, S Tavazoie, SI Lee, SM Waszak, SS Rao, T Lappalainen, T Michoel, TA Manolio, TF Mackay, The ENCODE, TS Furey, VG Cheung, W Cookson, W Zhang, Y Chen, Y Li   +102 more
core   +1 more source

Metabolomic systems biology of trypanosomes [PDF]

, 2010
Metabolomics analysis, which aims at the systematic identification and quantification of all metabolites in biological systems, is emerging as a powerful new tool to identify biomarkers of disease, report on cellular responses to environmental ...
BARBARA M. BAKKER, Cubbon, MICHAEL P. BARRETT, RAINER BREITLING, Shim   +4 more
core   +5 more sources

Evolutionary processes from the perspective of flowering time diversity. [PDF]

, 2020
Although it is well appreciated that genetic studies of flowering time regulation have led to fundamental advances in the fields of molecular and developmental biology, the ways in which genetic studies of flowering time diversity have enriched the field
Blackman, Benjamin K, Gaudinier, Allison
core   +1 more source

Toll Based Measures for Dynamical Graphs [PDF]

, 2007
Biological networks are one of the most studied object in computational biology. Several methods have been developed for studying qualitative properties of biological networks.
Bourdon, Jérémie, Eveillard, Damien
core   +2 more sources

Logic Integer Programming Models for Signaling Networks

, 2008
We propose a static and a dynamic approach to model biological signaling networks, and show how each can be used to answer relevant biological questions. For this we use the two different mathematical tools of Propositional Logic and Integer Programming.
Haus U.-U., Kathrin Niermann, Klaus Truemper, Robert Weismantel, Saez-Rodriguez J., Utz-Uwe Haus   +5 more
core   +3 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Synthetic biology—putting engineering into biology [PDF]

, 2006
Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
core   +1 more source