Results 11 to 20 of about 355,279 (98)

Language-based Abstractions for Dynamical Systems [PDF]

open access: yes, 2017
Ordinary differential equations (ODEs) are the primary means to modelling dynamical systems in many natural and engineering sciences. The number of equations required to describe a system with high heterogeneity limits our capability of effectively ...
Vandin, Andrea
core   +2 more sources

Logic Integer Programming Models for Signaling Networks

open access: yes, 2008
We propose a static and a dynamic approach to model biological signaling networks, and show how each can be used to answer relevant biological questions. For this we use the two different mathematical tools of Propositional Logic and Integer Programming.
Haus U.-U.   +5 more
core   +3 more sources

Systems biology in animal sciences [PDF]

open access: yes, 2011
Systems biology is a rapidly expanding field of research and is applied in a number of biological disciplines. In animal sciences, omics approaches are increasingly used, yielding vast amounts of data, but systems biology approaches to extract ...
Bannink, A.   +4 more
core   +3 more sources

Toll Based Measures for Dynamical Graphs [PDF]

open access: yes, 2007
Biological networks are one of the most studied object in computational biology. Several methods have been developed for studying qualitative properties of biological networks.
Bourdon, Jérémie, Eveillard, Damien
core   +2 more sources

Multi-omics integration reveals molecular networks and regulators of psoriasis. [PDF]

open access: yes, 2019
BackgroundPsoriasis is a complex multi-factorial disease, involving both genetic susceptibilities and environmental triggers. Genome-wide association studies (GWAS) and epigenome-wide association studies (EWAS) have been carried out to identify genetic ...
Arneson, Douglas   +5 more
core   +3 more sources

Quantum Genetics and Quantum Automata Models of Quantum-Molecular Evolution Involved in the Evolution of Organisms and Species [PDF]

open access: yes, 2012
Previous theoretical or general approaches to the problems of Quantum Genetics and Molecular Evolution are considered in this article from the point of view of Quantum Automata Theory first published by the author in 1971 and further developed in several
I. C. Baianu
core   +2 more sources

The role of Computer Aided Process Engineering in physiology and clinical medicine [PDF]

open access: yes, 2009
This paper discusses the potential role for Computer Aided Process Engineering (CAPE) in developing engineering analysis and design approaches to biological systems across multiple levels—cell signalling networks, gene, protein and metabolic networks ...
Allen, R., Bogle, I.D.L., Sumner, T.
core   +1 more source

Mathematics at the eve of a historic transition in biology

open access: yes, 2017
A century ago physicists and mathematicians worked in tandem and established quantum mechanism. Indeed, algebras, partial differential equations, group theory, and functional analysis underpin the foundation of quantum mechanism.
Wei, Guo-Wei
core   +2 more sources

Design, modeling and synthesis of an in vitro transcription rate regulatory circuit [PDF]

open access: yes, 2008
This paper describes the design, modeling and realization of a synthetic in vitro circuit that aims at regulating the rate of mRNA transcription. Two DNA templates are designed to interact through their transcripts, creating negative feedback loops that ...
Forsberg, Per-Ola   +2 more
core   +2 more sources

Data-driven modelling of biological multi-scale processes

open access: yes, 2015
Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales.
Hasenauer, Jan   +3 more
core   +1 more source

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