Results 31 to 40 of about 3,561 (165)

A metagenetic approach to determine the diversity and distribution of cyst nematodes at the level of the country, the field and the individual [PDF]

, 2015
This study was supported by the Scottish Society for Crop Research and The University of Leeds Sustainable Agriculture Bursary Fund. SE-vdA is supported by BBSRC grant BB/M014207/1.Distinct populations of the potato cyst nematode (PCN) Globodera pallida ...
Jones, John T., Blok, Vivian C., Eves-van den Akker, Sebastian, Urwin, Peter E, Urwin, Peter E., Jones, JT, Cock, Peter, Reid, A, Eves-van den Akker, S, Urwin, Peter, Blok, Vivian, Jones, John T, Cock, Peter J. A., Pickup, Jon, Lilley, Catherine J, Reid, Alex, Anderson, E, Blaxter, Mark, Jones, John, Lilley, Catherine J., Lilley, Catherine, Cock, Peter J A, Blok, Vivian C, Blok, VC, Blaxter, M, Cock, PJA, Lilley, CJ, Pickup, J, Urwin, PE, Anderson, Eric   +29 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Inbreeding and selection on sex ratio in the bark beetle Xylosandrus germanus [PDF]

, 2011
Background: Local Mate Competition (LMC) theory predicts a female should produce a more female-biased sex ratio if her sons compete with each other for mates.
Keller, Laurent, Christian Bernasconi, Keller, L., David M Shuker, Bernasconi, Christian, Katharina Peer, Peer Katharina, Bernasconi Christian, Shuker, D.M., Keller Laurent, Shuker David M, Peer, Katharina, Laurent Keller, Taborsky, M., Taborsky, Michael, Bernasconi, C., Shuker, David M., Peer, K., Taborsky Michael, Michael Taborsky   +19 more
core   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Evolution of Music by Public Choice [PDF]

, 2012
Music evolves as composers, performers, and consumers favor some musical variants over others. To investigate the role of consumer selection, we constructed a Darwinian music engine consisting of a population of short audio loops that sexually reproduce ...
Burt, A, Leroi, AM, MAUCH, M, MacCallum, RM   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Simultaneous failure of two sex-allocation invariants : implications for sex-ratio variation within and between populations [PDF]

, 2015
This research was supported by Wolfson College Cambridge (A.M.M.R.) and the Natural Environment Research Council (grant no. NE/K009524/1) (A.G.).Local mate competition (LMC) occurs when male relatives compete for mating opportunities, and may favour the ...
Rodrigues, Antonio, Gardner, Andy
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Genes, culture and agriculture : an example of human niche construction [PDF]

, 2012
K. N. Laland was supported by an ERC Advanced Grant (EVOCULTURE).Theory and empirical data from a variety of disciplines strongly imply that recent human history involves extensive gene-culture coevolution, much of it as a direct result of human ...
Laland, Kevin Neville, Kendal, J.R., Laland, K. N., Michael J. O’Brien, O'Brien, Michael, O\u27Brien, Michael J., Kevin N. Laland   +6 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source